Results 51 to 60 of about 1,697,700 (268)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Socio-Cultural Management JournalIntroduction. The armed conflict in Ukraine calls into question the achievements in sustainable development, environmental safety and international cooperation of European countries.
Nataliia Mohylevska +2 more
doaj +1 more source
Юг России: экология, развитие, 2014 . Features of national culture as component of culture of ethnos, and as phenomenon of social and historical and cultural life of the people are defined in the article.National artist of force of space felt in all that was for it considerable in nature ...
G. M. Gadzhinayev
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Two Australian genome assemblies expand the genomic blueprint of giant kelp
BMC GenomicsBackground Giant kelp, Macrocystis pyrifera (order Laminariales), occurs across the temperate coasts of the Northern and Southern Hemispheres and is at high risk from ocean warming. Few giant kelp forests remain across the Southeast Australian shelf, and
Hugo J. Scharfenstein +5 more
doaj +1 more source
SYSTEM ANALYSIS IN SOCIO-CULTURAL MANAGEMENT: THEORY, METHODOLOGY AND TECHNOLOGY
Socio-Cultural Management Journal, 2020 Introduction. The topicality of the article’ topic is due to the growing need for methodological and technological development of systems analysis in the transition of mankind to the information age, the complexity of social relations and the ...
Yaroslav Martynyshyn +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source