Results 171 to 180 of about 127,144 (313)

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

open access: yesAdvanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska   +14 more
wiley   +1 more source

eQTL Meta‐Analysis Reveals Conserved and Population‐Specific Regulatory Variation Underlying Nutritional Trait Evolution and Domestication in Tomato

open access: yesAdvanced Science, EarlyView.
A comprehensive meta‐analysis of expression quantitative trait loci (eQTLs) across five diverse tomato populations reveals a high‐resolution atlas of transcriptional regulation and uncovers conserved and population‐specific regulatory architectures underlying fruit nutritional quality traits, including flavonoids, sugars, organic acids, carotenoids ...
Jiantao Zhao   +14 more
wiley   +1 more source

Association of Hearing Impairment and Mortality in the National Health and Nutrition Examination Survey [PDF]

open access: yesJAMA Otolaryngology–Head & Neck Surgery, 2015
Kevin J, Contrera   +3 more
openaire   +2 more sources

Anthropometric reference data for children and adults, United States, 1988-1994; data from the third National Health and Nutrition Examination Survey (NHANES III) [PDF]

open access: yes
by Margaret A. McDowell, Cheryl D. Fryar, Cynthia L. Ogden, Division of Health and Nutrition Examination Surveys.Includes bibliographical references (p. 3).McDowell MA, Fryar CD, Ogden CL.

core  

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

National Health and Nutrition Examination Survey : 2021 Mobile Examination Center Audio-Computer Assisted Self Interview procedures manual

open access: yes
The Mobile Examination Center (MEC) Audio-Computer Assisted Self Interview (ACASI) consists of questionnaires on a variety of health-related topics, including socially sensitive behaviors.

core  

Home - About - Disclaimer - Privacy