Results 311 to 320 of about 447,403 (387)

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

Advanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji, Yongli Ye, Jiadi Sun, Lina Sheng, Jinyou Li, Jin Yang, Bing Wu, Yuting Wang, Xingxing Gao, Liang Luo, Jianfeng Ping, Yinzhi Zhang, Xiulan Sun   +12 more
wiley   +1 more source

DASH Diet Adherence and Cardiovascular-Kidney Metabolic Syndrome Stages: National Health and Nutrition Examination Survey 2011-2020. [PDF]

JACC Adv
Akubo C, Washington IE, Song S, Kramer-Johansen M, Rodriguez C, Olusola-Bello M, Gledhill S, Sullivan V, Commodore-Mensah Y, Ogungbe O.   +9 more
europepmc   +1 more source

Skullcapflavone II Inhibits SLC1A4‐Mediated L‐Serine Uptake and Promotes Mitochondrial Damage in Gastric Cancer

Advanced Science, EarlyView.
Skullcapflavone II (SkII) significantly alters serine metabolism in gastric cancer cells by directly targeting the L‐serine transporter SLC1A4, thereby inhibiting L‐serine uptake rather than de novo synthesis. This disruption of serine metabolism by SkII leads to increased oxidative stress and consequent mitochondrial damage.
Jing Zhao, Yu‐Bo Ma, Rui‐Hong Xia, Zheng‐Chen Jiang, Ying Zhou, Ya‐Nan Wang, Meng‐Yan Yang, Jing‐Jie Dai, Tao Zhu, Li‐Bin Pan, Li Yuan   +10 more
wiley   +1 more source

Association between various insulin resistance surrogates and gallstone disease based on national health and nutrition examination survey. [PDF]

Sci Rep
Gong R, Ding Y, Yang K, Meng X, Sun X.
europepmc   +1 more source

The GLP1R Agonist Semaglutide Inhibits Reactive Astrocytes and Enhances the Efficacy of Neural Stem Cell Transplantation Therapy in Parkinson's Disease Mice

Advanced Science, EarlyView.
Compared to transplantation of neural stem cells (NSCs) alone, the combined treatment of NSCs with semaglutide more effectively improves motor dysfunction in Parkinson's disease (PD) mice. This synergistic effect may result from semaglutide's ability to suppress microglial activation, thereby preventing the transformation of resting astrocytes into ...
Dan Song, Xiaoya Zou, Di Ma, Yuying Zhao, Tingting Liu, Bibiao Shen, Oumei Cheng   +6 more
wiley   +1 more source

Adjustment Formula for Harmonizing Triglyceride Values in the Korea National Health and Nutrition Examination Survey, 2005-2022. [PDF]

Ann Lab Med
Choi R, Seo JD, Cho EJ, Lee W, Yun YM.
europepmc   +1 more source

Targeting Intratumoral Copper Inhibits Tumor Progression via p62‐Mediated EZH2 Degradation and Potentiates Anti‐PD‐1 Immunotherapy in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
The authors find that by targeting intratumoral copper, they can enhance p62‐mediated ubiquitination of EZH2 at the Ub‐K63 site by suppressing copper binding to SMURF2, an E3 ligase of EZH2, leading to its autophagic degradation. This mechanism suppressed OSCC progression and potentiated anti‐PD‐1 immunotherapy, highlighting a potential new therapeutic
Xiaohu Lin, Wanling Chen, Bo Li, Zhang Zhao, Zhonglin Yu, Xu‐Yun Zhao, Xuan Zhou, Zhien Feng, Chengzhong Lin, Wei Cao   +9 more
wiley   +1 more source

A Mass Spectrometry Approach Reveals Fatty Acid Isomerism in Tomato Cold Tolerance

Advanced Science, EarlyView.
An enhanced mass spectrometry approach reveals fatty acids (FAs) and FA isomers that are critical for tomato cold tolerance. Applying specific FA isomers can partially rescue cold sensitivity in tomato mutant plants, highlighting the importance of FA isomers in plant cold stress adaptation.
Leelyn Chong, Hengxue Shi, Qirui Yu, Xiaoning Shi, Zhaoxing Jia, Ziyun Dong, Yu Xia, Yingfang Zhu   +7 more
wiley   +1 more source

Nutritional risk assessment using estimated usual nutrient intake in Korean adults: analysis of the 8th (2019-2021) Korea National Health and Nutrition Examination Survey data. [PDF]

Nutr Res Pract
Byeon W, Kim CI, Kwon SO, Yoon J, Huang L.   +4 more
europepmc   +1 more source