Results 91 to 100 of about 19,134,440 (286)
Advanced Science, EarlyView.ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao +5 more
wiley +1 more source
Do Mathematics, humour and teaching combine? [PDF]
, 2020 Mathematics is a very important school subject, but in many countries, such as Portugal and Spain, it has high levels of failure, together with low levels of student engagement.
Costa Lopes, Ana Maria, Menezes, Luís
core +1 more source
'Die Hard Level: Romanian' – Self-irony and Humour in English-Language Memes about Romanians
Open Library of HumanitiesThis article tackles the issue of Romanian national identity and stereotypes, drawing on the most recent research on digital forms of communication, more specifically, memes.
Lucia-Mihaela Grosu-Rădulescu
doaj +2 more sources
Pitreries nationales : Pousse mais pousse égal, une expérience de modernité vernaculaire québécoise
Mise au Point, 2017 This article deals with the cultural presence of comic actor Gilles Latulippe in Quebec during the Quiet Revolution. It focuses on Pousse mais pousse égal, a film neglected in the history of cinema of Quebec, in which Latulippe starred. Despite the actor’
Sacha Lebel
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo +14 more
wiley +1 more source
Advanced Science, EarlyView.L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen +17 more
wiley +1 more source
Recontextualizing Brexit: Discursive Representations from Outside the UK
Critical Approaches to Discourse Analysis across Disciplines, 2021 In this introduction, we review the previous literature, present mostly in political science, on how Brexit has been perceived, discussed and instrumentalized outside of the UK.
Monika Brusenbauch Meislová +3 more
doaj
Advanced Science, EarlyView.Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
The Sidonian section of the Φιλόγελως [PDF]
, 2016 The Φιλόγελως is a Greek anthology of humour. One of its sections testifies that Sidonian people had a reputation for foolishness which is otherwise unattested.
Minunno, Giuseppe
core
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Advanced Science, EarlyView.Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source