Results 91 to 100 of about 727,997 (259)

Wellbeing and national identity in three generations of Czech and Slovak Holocaust survivors. [PDF]

Front Behav Neurosci, 2022
Preiss M, Fňašková M, Nečasová M, Heissler R, Bob P, Prokopová A, Šamánková D, Sanders E, Rektor I.   +8 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Encouraging gender-inclusive acceptance of multipurpose national-identity smart cards. [PDF]

PLoS One, 2022
Yee Yen Y, Yeow PHP, Wee Hong L.
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

National Identity in International Relations

Czech Journal of International Relations, 2017
The article interprets the role of national identity in contemporary international relations scholarship. It distinguishes two main approaches – the social constructivist and post-structural approaches – and shows their deficiencies.
Michal Kolmaš
doaj  

How China's Great Bay Area Policies Affect the National Identity of Hong Kong Youth-A Study of a Quasi-Natural Experiment Based on the Difference-in-Differences Model. [PDF]

Behav Sci (Basel), 2023
Fu C, Liao L, Mo T, Chen X.
europepmc   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Images of “the Republican Citizen” Designed in the Context of National Identity Construction in Türkiye during the Early Republican Period

Yakın Dönem Türkiye Araştırmaları
In the 19th century, as a result of certain economic, political, and social changes, the model of the nation-state came to replace that of the multinational empire.
Hadiye Yılmaz Odabaşı, Deniz Ülke Arıboğan   +1 more
doaj   +1 more source

Dutch national identity in a majority-minority context: when the dominant group becomes a local minority. [PDF]

J Ethn Migr Stud, 2023
Lazëri M, Coenders M.
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source