Results 71 to 80 of about 727,997 (259)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
National Identity and Architectural Expression
Hungarian Cultural StudiesThe interior design of a building provides critical insights into its historical and cultural context. This study examines the architectural and symbolic relationships among two Nationality and Heritage Rooms in the Cathedral of Learning—the Yugoslav ...
Éva Lovra
doaj +1 more source
National identity and global culture
Academicus International Scientific Journal, 2010 Somalia has been one of the UN member countries who lingers from the presence of terrorist groups in its territory, that exert tremendous influence in the daily life of its society and economy. Al Shabaab is well known in the horn of Africa, particularly
Michele Marsonet
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
La región: del imperio jerifiano al Marruecos actual
Revista de Estudios Internacionales Mediterráneos, 2010 This article deals with the identity concept in Morocco. The author thinks about the possibility of talking about national identity in Morocco, a place far away from the Greco-Judeo-Christian space where the concept of nation has been created. The author
Zarrouk, Mourad
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
An Analysis of National Identity and its Sextet Dimensions in Isfahan City
جامعه شناسی کاربردی, 2013 Introduction Entering the twenty-first century, the world witnessed several major developments that affect all aspects of human life, and in the midst of one of the most challenging changes, it is a change in the cognitive dimension and more precisely ...
Ali Rabbani, Yaser Rastegar
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