Results 11 to 20 of about 288,801 (266)

National Strategic Computing Initiative [PDF]

open access: yesComputing in Science & Engineering, 2018
The National Strategic Computing Initiative (NSCI) was initiated in 2015 by then-US President Barack Obama, with the goal of accelerating scientic discovery and economic competitiveness by maximizing the benets of high-performance computing (HPC) research, development, and deployment. This special issue presents four papers that illustrate the state of
Rudi Eigenmann, Barry I. Schneider
openaire   +1 more source

TULIP: An RNA-seq-based Primary Tumor Type Prediction Tool Using Convolutional Neural Networks

open access: yesCancer Informatics, 2022
Background: With cancer as one of the leading causes of death worldwide, accurate primary tumor type prediction is critical in identifying genetic factors that can inhibit or slow tumor progression.
Sara Jones   +7 more
doaj   +1 more source

Upregulated endonuclease Regnase-1 suppresses osteoarthritis by forming a negative feedback loop of catabolic signaling in chondrocytes

open access: yesArthritis Research & Therapy, 2021
Background Ribonucleases (RNases) play central roles in the post-transcriptional regulation of mRNA stability. Our preliminary results revealed that the endonuclease Regnase-1 is specifically upregulated in osteoarthritic chondrocytes. We herein explored
Jeong-In Yang, Jang-Soo Chun
doaj   +1 more source

Agro-morphological diversity of Nepalese naked barley landraces

open access: yesAgriculture & Food Security, 2018
Background Naked barley is a traditional, climate-resilient and highly nutritious crop of the high mountains of Nepal. Knowledge of agro-morphological diversity among the naked barely genotypes is fundamental for their efficient utilization in plant ...
Ritesh Kumar Yadav   +8 more
doaj   +1 more source

Michal Miloslav Hodža: his national-emancipation and political initiatives [PDF]

open access: yesStudia Politica Slovaca, 2021
The professional ambition of the study is to present the ethnic-emancipatory and national-political initiatives of Michal Miloslav Hodža, one of the representatives of the Slovak national movement in the revolutionary years of 1848-1849, co-creator of ...
Marcela Gbúrová
doaj   +1 more source

Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy

open access: yesNature Communications, 2020
Epigenetic regulations of autophagy have emerged as mechanisms for maintaining cellular homeostasis. Here the authors reveal that the CARM1-Pontin-FOXO3a signaling axis can activate autophagy related genes through enhancer activation.
Young Suk Yu   +11 more
doaj   +1 more source

Adipocytes Are the Control Tower That Manages Adipose Tissue Immunity by Regulating Lipid Metabolism

open access: yesFrontiers in Immunology, 2021
Accumulating evidence reveals that adipose tissue is an immunologically active organ that exerts multiple impacts on the regulation of systemic energy metabolism.
Jeu Park   +20 more
doaj   +1 more source

Diversity sourcing of foxtail millet through diversity assessment and on-farm evaluation

open access: yesCogent Food & Agriculture, 2018
Drawing upon the serious food insecurity issues and continually growing impacts of climate change on livelihood, diversity sourcing of climate-resilient, nutritionally rich crops like foxtail millet through diversity assessment and on-farm evaluation ...
Ritesh Kumar Yadav   +4 more
doaj   +1 more source

Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes

open access: yesNature Communications, 2017
The pathogenesis of osteoarthritis is unclear. The authors show that estrogen-related receptor gamma is upregulated in cartilage from patients and mouse models, where it drives production of matrix-degrading MMPs in chondrocytes, and that its ...
Young-Ok Son   +10 more
doaj   +1 more source

Newer initiatives under national tuberculosis elimination programme [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2023
National Tuberculosis Elimination Programme (NTEP) is a Centrally Sponsored Scheme being implemented under the aegis of the National Health Mission with resource sharing between the State Governments and the Central Government.
Anugraha John   +3 more
doaj  

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