Results 101 to 110 of about 2,131,183 (309)

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

How to Improve the Supportive Role of Estonian Innovation System toward Launching New Products by High Technology Companies?

open access: yesEesti Majanduspoliitilised Väitlused, 2009
The purpose of the study is to evaluate how supportive is Estonian national innovation system toward the launching of new innovative products by high technology firms.
Liisi Sepp, Urmas Varblane
doaj   +1 more source

National Innovation System in the Era of Liberalization: Implications for Science and Technology Policy for Developing Economies [PDF]

open access: yes
The national system of innovations in the recent phase of globalization has undergone dramatic structural transformation. Innovations entails organizational as well as changes in the rules of the game.
Singh, Baldev, Singh, Lakhwinder
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

The role of technology centers in regional competitiveness: a multicriteria approach

open access: yesRevista de Estudios Empresariales. Segunda Época, 2023
Countries adopt different policies and strategies to boost regional growth and competitiveness. R&D is one of the most important drivers of national competitiveness because of its ability to generate knowledge and convert that knowledge into useful ...
Cristina del Campo   +3 more
doaj  

ERAWATCH Country Reports 2013: Austria [PDF]

open access: yes, 2014
The Analytical Country Reports analyse and assess in a structured manner the evolution of the national policy research and innovation in the perspective of the wider EU strategy and goals, with a particular focus on the performance of the national ...
CUNTZ Alexander
core   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

New Processes and New Products in Europe and Italy [PDF]

open access: yes
This article investigates the differences in the mechanisms and strategies conducing to the introduction of new processes and products in Italy and Europe.
Francesco Crespi, Mario Pianta
core  

Determinants of cooperation with institutional partners and innovation - performance of Polish manufacturing enterprises. Research outcomes [PDF]

open access: yes, 2013
The aim of this paper is to assess of the influence of institutional cooperation (with research institutes and universities) on the innovation performance of companies as well as determinants of such cooperation.
Lewandowska, Małgorzata Stefania
core  

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