Results 81 to 90 of about 35,883,944 (304)

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

National Innovation System in the Era of Liberalization: Implications for Science and Technology Policy for Developing Economies [PDF]

open access: yes
The national system of innovations in the recent phase of globalization has undergone dramatic structural transformation. Innovations entails organizational as well as changes in the rules of the game.
Singh, Lakhwinder, Singh, Baldev
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Mapping National Innovation Systems in the OECD Area [PDF]

open access: yes
The purpose of this paper is to present new findings about the structure and the organization of innovative activities in selected OECD countries.
Andreas Pyka, Markus Balzat
core  

Australian innovation system report 2013 [PDF]

open access: yes, 2013
Australian innovation and engagement with Asia is the theme of the Australian Innovation System Report 2013, the fourth in a series of Australian Government reports on the Australian innovation system.

core  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

National innovation system, competitiveness and economic growth [PDF]

open access: yes
Differences in income-elasticities of imports and exports among countries bring about distinct degrees of external constraints to growth. This argument has been pointed out by Prebisch and by authors in the Kaldorian tradition.
Daniela Almeida Raposo Torres   +1 more
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

India's National Innovation System: Key elements and corporate perspectives [PDF]

open access: yes
In recent years India has emerged as a major destination for corporate research and development (R&D), especially for multinational corporations.
Buse, Stephan   +2 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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