Results 51 to 60 of about 3,915,605 (312)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

AB’ye Üyelik Sürecinde Türk Medyası

open access: yesAnkara Avrupa Çalışmaları Dergisi, 2009
Bu çalışmada, Avrupa Birliği–Türkiye ilişkilerinin medyada temsili, haber üretim süreçlerindeki dönüşüm dikkate alınarak incelenmektedir. AB ile ilişkiler ve haber medyasında bu ilişkilerin kurulma ve tartışılma biçimleri ele alınırken, “ulusal çıkar ...
Ayşe İnal, Tezcan Durna
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Are Ambassadors Creators or just Executors of the National Interests? George Frost Kennan and the 1961 Non-Aligned Conference in Belgrade [PDF]

open access: yesMeđunarodni Problemi
Džordž Frost Kenan bio je jedan od najpoznatijih spoljnopolitičkih mislilaca i stratega u razdoblju Hladnog rata. Međutim, u pogledu praktičnih dostignuća bio je daleko manje uspešan.
Saša Mišić, Dragan Živojinović
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

National interest implementation Matrix: Evaluating and measuring Serbia’s achievements [PDF]

open access: yesMeđunarodni Problemi
Ovaj rad razvija metodološku matricu za merenje ostvarenosti/stepena uspešnog sprovođenja nacionalnog interesa Republike Srbije. Teorijska osnova ovog indeksa je „tanki” konstruktivizam u međunarodnim odnosima, koji se zasniva na ontološkom ...
Milan Krstić, Nikola Jović
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

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