Results 71 to 80 of about 4,328,152 (304)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà +11 morewiley +1 more sourceRUSSIAN – UKRAINE WAR: IMPLICATIONS ONAFRICAN EXTERNAL RELATIONS
Journal of Contemporary Society Education, 2021 In international politics, the national interest of a nation is pertinent. The ongoing war between Russia and
Ukraine is nothing short of that. Since the collapse of the erstwhile Soviet Union, the West has been making
considerable effort to weaken ...RAJI, Adesina Abdulfattah Ph.D.doaj Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales +11 morewiley +1 more sourceFraming the Falklands/Malvinas War: National interest in the coverage of The London Times, La Nación (Argentina) and El Mercurio (Chile)</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Universum</i>, 2004 </span><br><span class="r_content">El objetivo de este trabajo es analizar el enfoque editorial con que los diarios La Nación, Argentina, El Mercurio, Chile, y The London Times, Gran Bretaña, presentaron la cobertura de la guerra de Malvinas (1982), y el rol que jugó en las decisiones ...</span><br><span class="r_sub"><i>Marina Walker</i></span><br><small><a href="https://doaj.org/article/9b55f79d12e44b6b93cbe61f4a2eac9b" target="_blank" rel="nofollow" title="doaj.org/article/9b55f79d12e44b6b93cbe61f4a2eac9b">doaj</a> </small> <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.22146/jsp.41709" target="_blank" rel="nofollow">Assessing the Evolution of Maritime Strategy in the Asia Pacific</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>JSP: Jurnal Ilmu Sosial dan Ilmu Politik</i>, 2019 </span><br><span class="r_content">The end of the Cold War has provided an opportunity for scholars to do an in-depth study on the concept of maritime security, especially in the Asia Pacific region.</span><br><span class="r_sub"><i>Buddy Suseto<span id="ma_7" style="display:none">, Zarina Othman, Farizal Mohd Razalli</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+2 more</a></small></i></span><br><small><a href="https://doaj.org/article/614401f932d643f4a9bb827fc11f20c0" target="_blank" rel="nofollow" title="doaj.org/article/614401f932d643f4a9bb827fc11f20c0">doaj</a> </small> <div id="more_7" style="display:none"><a href="/sci_redir.php?doi=10.22146%2Fjsp.41709" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.22146/jsp.41709'); alert('Copied the doi');">copy doi</a> <small>(10.22146/jsp.41709)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_7')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70235" target="_blank" rel="nofollow">CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.</span><br><span class="r_sub"><i>Aya Saleh<span id="ma_8" style="display:none">, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+12 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70235?mi=2or9o2m&af=R&AllField=national interest&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70235?mi=2or9o2m&af=R&AllField=national interest&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70235" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70235'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70235)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.31957/pjdir.v5i1.4308" target="_blank" rel="nofollow">South-South Cooperation and Indonesia’s National Interests</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Papua Journal of Diplomacy and International Relations</i></span><br><span class="r_content">South-South Cooperation (SSC) is one of the outcomes of the Ten Bandung Principles agreement which became the basis for the Non-Aligned Movement. As one of the initiators of the Non-Aligned Movement, Indonesia views SSC as being in line with the spirit ...</span><br><span class="r_sub"><i>Albert Triwibowo<span id="ma_9" style="display:none">, Aknolt Kristian Pakpahan, Stanislaus Risadi Apresian</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+2 more</a></small></i></span><br><small><a href="https://doaj.org/article/a60cbe6567964531a6781dfc8ab27faf" target="_blank" rel="nofollow" title="doaj.org/article/a60cbe6567964531a6781dfc8ab27faf">doaj</a> </small> <div id="more_9" style="display:none"><a href="/sci_redir.php?doi=10.31957%2Fpjdir.v5i1.4308" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.31957/pjdir.v5i1.4308'); alert('Copied the doi');">copy doi</a> <small>(10.31957/pjdir.v5i1.4308)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_9')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/1878-0261.70236" target="_blank" rel="nofollow">E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Molecular Oncology, EarlyView.</i></span><br><span class="r_content">Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...</span><br><span class="r_sub"><i>Sergei Chuikov<span id="ma_10" style="display:none">, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_10')">+3 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/1878-0261.70236?mi=2or9o2m&af=R&AllField=national interest&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/1878-0261.70236?mi=2or9o2m&af=R&AllField=national interest&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F1878-0261.70236" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/1878-0261.70236'); alert('Copied the doi');">copy doi</a> <small>(10.1002/1878-0261.70236)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-foreign_policy/" class="suggestion"onclick="show_loader();"><b>foreign policy</b></a><br/><a href="/q-science/" class="suggestion"onclick="show_loader();"><b>science</b></a><br/><a href="/q-united_states/" class="suggestion"onclick="show_loader();"><b>united states</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-covid-19/" class="suggestion"onclick="show_loader();"><b>covid-19</b></a><br/><a href="/q-national_security/" class="suggestion"onclick="show_loader();"><b>national security</b></a><br/><a href="/q-diplomacy/" class="suggestion"onclick="show_loader();"><b>diplomacy</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-vaccination/" class="suggestion"onclick="show_loader();"><b>vaccination</b></a><br/></div></div></div><div class="pagenav"><a href="/q-national_interest/p-7/" rel="nofollow"><b>previous</b></a> <a href="/q-national_interest/p-6/" rel="nofollow">6</a> <a href="/q-national_interest/p-7/" rel="nofollow">7</a> <b>8</b> <a href="/q-national_interest/p-9/" rel="nofollow">9</a> <a href="/q-national_interest/p-10/" rel="nofollow">10</a> <a href="/q-national_interest/p-9/" id="next" rel="nofollow"><b>next</b></a> </div><br></div>
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