Results 101 to 110 of about 4,688,224 (312)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Power it's in the middle of the international system. The behavior of each state and the dynamism of the international system rise in the structure and the distribution of the global power.
Adina Elena Sandu, Ciprian Roscaneanu
doaj
Elections, special interests, and the fiscal costs of financial crisis [PDF]
The author proposes a new approach to explain why the costs of crisis are greater in some countries than in others. He begins with the premise that many crises result from the willingness of politicians to cater to special interests, at the expense of ...
Keefer, Philip
core
Measuring national interests in the international coffee agreement [PDF]
This article shows how national interests in price-changing international commodity agreements can be measured. Two approaches are distinguished.
Herrmann, Roland
core
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
The Pertinence of the Regionalization Project in Romania
The concept of “unified” or “homogeneous” state authority (in which the local authorities act as representatives of the central government, equivocally subordinated to its directive and control)was rejected and replaced with a dual system, in which the ...
Mihaela CARAUSAN
doaj
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
Ukraine’s policy in Afghanistan
The article investigates the process of evolution of Ukraine’s foreign policy in Afghanistan. The author determines the national interests of Ukraine in this state and describes the main stages of cooperation in political, military and economic spheres ...
K Petrovich Kurylev
doaj
Nuclear power in New Zealand: Attitudes and prospects [PDF]
Traditional New Zealand attitudes with regard to all things nuclear are subjected to critical scrutiny. It is argued that these may frequently lead us to take policy positions that do not best serve our national interests.
Smith, Ron C.
core +1 more source
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source

