Results 121 to 130 of about 4,702,823 (311)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Rethinking White Supremacy: who counts in 'Whiteworld' [PDF]
, 2006 The article addresses the nature of power relations that sustain and disguise white racial hegemony in contemporary ‘western’ society. Following the insights offered by critical race theory (CRT), white supremacy is conceived as a comprehensive condition
Gillborn, David
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Soft and Hard Strategies: The Role of Business in the Crafting of International Commercial Law [PDF]
, 2019 Part I returns to the classic definition of hard international law initially put forward by Kenneth Abbott and Duncan Snidal and related IR scholars and analyzes existing commercial law treaties in light of this definition.
Susan Block-Lieb
core +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Fixing Australia’s incredible defence policy [PDF]
Australia’s new government must make tough decisions in defence policy. Australia’s broad national interests and the challenging strategic environment in Indo-Pacific Asia make it essential to modernise the Australian Defence Force.
James Brown, Rory Medcalf
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The Making of an Integrated National Grain Market in China [PDF]
, 2001 A market economy will not emerge from a redistributive economy automatically once the state abolishes a redistributive system. Because of the cognitive incompleteness of market actors in post-redistributive societies, and also because of the conflicts ...
Zhou, Wubiao
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Safeguarding and looked after children: national results for third sector organisations survey 2010 (NAT ’10) [PDF]
, 2010 "This is Ofsted’s first annual survey of third sector organisations representing the interests of, or providing services for children and young people in every local authority in England. The third sector survey was conducted at the same time as a survey
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source