Results 131 to 140 of about 23,476,482 (299)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Constructing national interests : narrating the Falklands crisis

open access: yes, 2012
This thesis solves the puzzle of why Britain fought the Falklands war. It situates the loss of the Falkland Islands colony in a particular historical context in which the constitutive role of ideas can be examined specifically in relation to interests ...
Chou, Shih-Yu
core  

Nations: Formation and Interest Dynamics

open access: yesRUDN journal of Sociology, 2012
The article gives a brief description of historic conditions leading to the formation of nations, and on the basis of attributive features of a nation the set of national interests is identified.
A E Kafirin
doaj  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

"Associations matter: reconsidering the political strategies of firms in the European Union" [PDF]

open access: yes, 2007
[From the introduction]. This paper tries to understand whether the EU system of interest representation is indeed Americanizing. How important are sector-wide groups at the European and at the national level for the political activities of their members?
Woll, Cornelia., Grossman, Emiliano,
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

National Commission on Military, National, and Public Service: Interim Report Executive Summary

open access: yes, 2019
Executive summary for the interim report of the National Commission on Military, National, and Public Service outlining their charge, findings from information-gathering, and areas for further research, with social media contacts for public ...
United States. National Commission on Military, National, and Public Service.
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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