Results 131 to 140 of about 4,702,823 (311)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The mechanisms of ensuring of Russian national interests in the information sphere

open access: yesRUDN Journal of Law, 2010
The article researches some actual questions of ensuring of Russian national interests in the information sphere. It represents an analysis of such terms as «national security», «information security», «national interests».
N N Kunyaev
doaj  

Strategic interests and Australian grand strategy [PDF]

open access: yes
The newly-released National Security Strategy provides good coverage of broad security issues, but could have given a more expansive worldview. Previous Defence White Papers have shown our approach to national security interests has been narrow and ...
Hayley Channer, Rod Lyon
core  

Regional Security Organizations and National Interests: Analyzing the NATO-Greek Relationship [PDF]

open access: yes, 1988
This article analyzes the reasons which account for Greece\u27s continuing membership in the Atlantic Alliance, even though NATO has not lived up to expectations and has failed to protect the nation\u27s security against threats from Turkey.
Danopoulos, Constantine P.
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

The Human Spirit in Lagaan: Once Upon a Time in India [PDF]

open access: yes, 2008
In as much as film can be considered a modern-day corollary to these forms of rhetoric, one could conclude that certain movies—advertently or inadvertently—perpetuate cultural identities and solidify national interests as well.
Crossman, Britt
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

NATIONAL SECURITY OF RUSSIA AND INNOVATIVE DEVELOPMENT TASKS

open access: yesAdvanced Engineering Research, 2011
The current state of the national security of Russia is analyzed. Paramount tasks of the national policy in the field of the innovative development of the country aimed at its general economic security upgrade are specified.
Olga A. Mironova
doaj  

Producers’ perceptions of public good agricultural practices and their pesticide use: The case of MyGAP for durian farming in Pahang, Malaysia [PDF]

open access: yes, 2017
This paper investigates the local implementation of Malaysian public GAP standard called MyGAP by examining its effectiveness in raising the awareness and improving the pesticide use practices of participant smallscale ...
Ng, Chuck Chuan
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy