Results 121 to 130 of about 4,688,224 (312)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Nations: Formation and Interest Dynamics
RUDN journal of Sociology, 2012 The article gives a brief description of historic conditions leading to the formation of nations, and on the basis of attributive features of a nation the set of national interests is identified.
A E Kafirin
doaj
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Rethinking White Supremacy: who counts in 'Whiteworld' [PDF]
, 2006 The article addresses the nature of power relations that sustain and disguise white racial hegemony in contemporary ‘western’ society. Following the insights offered by critical race theory (CRT), white supremacy is conceived as a comprehensive condition
Gillborn, David
core +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Soft and Hard Strategies: The Role of Business in the Crafting of International Commercial Law [PDF]
, 2019 Part I returns to the classic definition of hard international law initially put forward by Kenneth Abbott and Duncan Snidal and related IR scholars and analyzes existing commercial law treaties in light of this definition.
Susan Block-Lieb
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Fixing Australia’s incredible defence policy [PDF]
Australia’s new government must make tough decisions in defence policy. Australia’s broad national interests and the challenging strategic environment in Indo-Pacific Asia make it essential to modernise the Australian Defence Force.
James Brown, Rory Medcalf
core
The Human Spirit in Lagaan: Once Upon a Time in India [PDF]
, 2008 In as much as film can be considered a modern-day corollary to these forms of rhetoric, one could conclude that certain movies—advertently or inadvertently—perpetuate cultural identities and solidify national interests as well.
Crossman, Britt
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source