THE POLICY FOR THE SOCIAL PARTICIPATION IN CONSERVATION: CASE STUDY [PDF]
Colombia is one the world´s richest countries in biological resources. To protect them, Colombian Law created the National Parks in 1959. Further regulations for their creation and administration were approved during the seventies.
Eduardo Uribe
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Current foreign policy threats: anxieties and fears of student youth
Известия высших учебных заведений. Поволжский регион: Общественные наукиBackground. To ensure countryʼs national security, comprehensive analysis of current and real threats, which can have significant impact on sovereignty, integrity and progressive development of the country is needed.
L.V. Rozhkova +3 more
doaj +1 more source
Interpreting nonsignificant findings: Reassessing the safety of self-locking standalone cages in octogenarian patients undergoing ACDF. [PDF]
J Orthop TraumatolAbudayeh A, Fishchenko I.
europepmc +1 more source
The New Face of Chinese Industrial Policy: Making Sense of Anti-Dumping Cases in the Petrochemical and Steel Industries [PDF]
Why have China's petrochemical and steel industries behaved so differently in seeking trade protection through antidumping measures? We argue that the patterning of antidumping actions is best explained in terms of the political economy of economic ...
Regina M. Abrami, Yu Zheng
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
US new playbook for global health: balancing national interest and global responsibility. [PDF]
BMJ Glob HealthAremu SO +6 more
europepmc +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Correction: Data integrity issues: catalyst for a more robust approach to research on perioperative oxygen therapy? [PDF]
Perioper Med (Lond)Oldman AH +3 more
europepmc +1 more source