Results 91 to 100 of about 1,333,689 (304)

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Exploring and retrieving sequence and metadata for species across the tree of life with NCBI Datasets

Scientific Data
To explore complex biological questions, it is often necessary to access various data types from public data repositories. As the volume and complexity of biological sequence data grow, public repositories face significant challenges in ensuring that the
Nuala A. O’Leary, Eric Cox, J. Bradley Holmes, W. Ray Anderson, Robert Falk, Vichet Hem, Mirian T. N. Tsuchiya, Gregory D. Schuler, Xuan Zhang, John Torcivia, Anne Ketter, Laurie Breen, Jonathan Cothran, Hena Bajwa, Jovany Tinne, Peter A. Meric, Wratko Hlavina, Valerie A. Schneider   +17 more
doaj   +1 more source

Expert retrieval assistance development and experimentation [PDF]

, 1988
Caption title.Bibliography: leaves 8-9.Supported, in part, by a grant from the National Library of Medicine. LM-03210 Supported, in part, by a grant from the National Science Foundation.

core  

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

AlphaFold predictions of fold-switched conformations are driven by structure memorization

Nature Communications
Recent work suggests that AlphaFold (AF)–a deep learning-based model that can accurately infer protein structure from sequence–may discern important features of folded protein energy landscapes, defined by the diversity and frequency of different ...
Devlina Chakravarty, Joseph W. Schafer, Ethan A. Chen, Joseph F. Thole, Leslie A. Ronish, Myeongsang Lee, Lauren L. Porter   +6 more
doaj   +1 more source

Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov, Alexander F. Santillo, Patrick R. Hof   +2 more
wiley   +1 more source

Expanding the Legacy: The National Library of Medicine Michael E. DeBakey Lecture in the History of Medicine. [PDF]

Methodist Debakey Cardiovasc J, 2022
Reznick JS, Koyle KM.
europepmc   +1 more source

Making Sense of Dietary Supplements: The Dietary Supplements Labels Database [PDF]

, 2008
This article describes the Dietary Supplements Labels Database, a new resource from the National Library of Medicine that integrates information from dietary supplement manufacturers, government agencies, and clinical research into an easy-to-use ...
Healy, Annette M.
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Future advancement of health care through standardized nursing terminologies: reflections from a Friends of the National Library of Medicine workshop honoring Virginia K. Saba. [PDF]

J Am Med Inform Assoc, 2023
Dunn Lopez K, Heermann Langford L, Kennedy R, McCormick K, Delaney CW, Alexander G, Englebright J, Carroll WM, Monsen KA.   +8 more
europepmc   +1 more source