Results 21 to 30 of about 1,345,097 (304)

Ribovore: ribosomal RNA sequence analysis for GenBank submissions and database curation

open access: yesBMC Bioinformatics, 2021
Background The DNA sequences encoding ribosomal RNA genes (rRNAs) are commonly used as markers to identify species, including in metagenomics samples that may combine many organismal communities.
Alejandro A. Schäffer   +7 more
doaj   +1 more source

Strengthening and stretching for rheumatoid arthritis of the hand (SARAH). A randomised controlled trial and economic evaluation [PDF]

open access: yes, 2015
Study registration: Current Controlled Trials ISRCTN 89936343.Background - The effectiveness of exercise for improving hand and wrist function in people with rheumatoid arthritis (RA) is uncertain.
  +128 more
core   +2 more sources

A Systematic Evaluation of Ensemble Learning Methods for Fine-Grained Semantic Segmentation of Tuberculosis-Consistent Lesions in Chest Radiographs

open access: yesBioengineering, 2022
Automated segmentation of tuberculosis (TB)-consistent lesions in chest X-rays (CXRs) using deep learning (DL) methods can help reduce radiologist effort, supplement clinical decision-making, and potentially result in improved patient treatment.
Sivaramakrishnan Rajaraman   +4 more
doaj   +1 more source

In Search of an Audience: Popular Pharmacies and the Limits of Literate Medicine in Late Seventeenth- and Early Eighteenth-Century Russia. [PDF]

open access: yes, 2015
This article addresses the question of the limits of literate medicine in Europe, through an examination of the Russian literate medical world of the late seventeenth and early eighteenth centuries.
Griffin, Clare
core   +4 more sources

ElasticBLAST: accelerating sequence search via cloud computing

open access: yesBMC Bioinformatics, 2023
Background Biomedical researchers use alignments produced by BLAST (Basic Local Alignment Search Tool) to categorize their query sequences. Producing such alignments is an essential bioinformatics task that is well suited for the cloud.
Christiam Camacho   +4 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Iran National Digital Library of Medicine: Pros and Cons [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2008
Iran National Digital Library of Medicine was launched in 2008 by Shahid Beheshti University of Medical Sciences in order to supply English language scientific resources for the Universities of Medical Sciences throughout the country.
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doaj  

Putative Host-Derived Insertions in the Genomes of Circulating SARS-CoV-2 Variants

open access: yesmSystems, 2022
Insertions in the SARS-CoV-2 genome have the potential to drive viral evolution, but the source of the insertions is often unknown. Recent proposals have suggested that human RNAs could be a source of some insertions, but the small size of many ...
Yiyan Yang   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Eradicating Polio: 50 Years of Vaccines [PDF]

open access: yes, 2005
https://digitalcommons.cwu.edu/government_posters/1156/thumbnail ...
United States National Library of Medicine
core   +1 more source

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