Results 51 to 60 of about 1,333,689 (304)

Deep learning with sentence embeddings pre-trained on biomedical corpora improves the performance of finding similar sentences in electronic medical records

open access: yesBMC Medical Informatics and Decision Making, 2020
Background Capturing sentence semantics plays a vital role in a range of text mining applications. Despite continuous efforts on the development of related datasets and models in the general domain, both datasets and models are limited in biomedical and ...
Qingyu Chen   +4 more
doaj   +1 more source

El uso de BITNET para acceder a las bases de datos de la Biblioteca Nacional de Medicina [PDF]

open access: yes, 1994
This article describes a project developed using GRATEFUL MED, a software of the National Library of Medicine (NLM) in BITNET Network to access to data bases of ...
Gamboa, Carlos A., Hsieh, Richard K. C.
core  

Seizure-induced basal dendrites on granule cells [PDF]

open access: yes, 2010
Seizure-induced hilar basal dendrites on dentate granule cells are observed in several rodent models of temporal lobe epilepsy. Ultrastructural evidence showed that basal dendrites receive predominantly excitatory synapses, including many from mossy ...
Buckmaster, PS   +7 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Semantic annotation of consumer health questions

open access: yesBMC Bioinformatics, 2018
Background Consumers increasingly use online resources for their health information needs. While current search engines can address these needs to some extent, they generally do not take into account that most health information needs are complex and can
Halil Kilicoglu   +6 more
doaj   +1 more source

A Computational Approach for Identifying Plant-Based Foods for Addressing Vitamin Deficiency Diseases [PDF]

open access: yes, 2015
Vitamins are nutrients that are essential to human health, and deficiencies have been shown to cause severe diseases. In this study, a computational approach was used to identify vitamin deficiency diseases and plant-based foods with vitamin content ...
Sarkar, Indra Neil, Yu, Christina
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

On the development of three new tools for organizing and sharing information in three-dimensional electron microscopy [PDF]

open access: yes, 2013
This work was funded by the Spanish Ministerio de Economía y Competividad through grants BFU2009-09331, BIO2010-16566, ACI2009-1022, ACI2010-1088 and AIC-A- 2011-0638, by the Comunidad Autonoma de Madrid through grant S2010/BMD-2305, by NFS grant No.
Carazo García, Jose María   +5 more
core   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

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