Results 61 to 70 of about 473,849 (247)

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Exploring and retrieving sequence and metadata for species across the tree of life with NCBI Datasets

Scientific Data
To explore complex biological questions, it is often necessary to access various data types from public data repositories. As the volume and complexity of biological sequence data grow, public repositories face significant challenges in ensuring that the
Nuala A. O’Leary, Eric Cox, J. Bradley Holmes, W. Ray Anderson, Robert Falk, Vichet Hem, Mirian T. N. Tsuchiya, Gregory D. Schuler, Xuan Zhang, John Torcivia, Anne Ketter, Laurie Breen, Jonathan Cothran, Hena Bajwa, Jovany Tinne, Peter A. Meric, Wratko Hlavina, Valerie A. Schneider   +17 more
doaj   +1 more source

Prediction of the incubation period for COVID-19 and future virus disease outbreaks

BMC Biology, 2020
Background A crucial factor in mitigating respiratory viral outbreaks is early determination of the duration of the incubation period and, accordingly, the required quarantine time for potentially exposed individuals. At the time of the COVID-19 pandemic,
Ayal B. Gussow, Noam Auslander, Yuri I. Wolf, Eugene V. Koonin   +3 more
doaj   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Die Deutsche Zentralbibliothek für Medizin in Köln und Bonn – Zentrale Fachbibliothek und Infrastruktureinrichtung für die Forschung in der Bundesrepublik Deutschland / The German National Library of Medicine in Cologne and Bonn – National Library and Infrastructure Organisation for Research in the Federal Republic of Germany

GMS Medizin – Bibliothek – Information, 2009
The German National Library of Medicine (ZB MED) is the National Library for Medicine, Health, Nutrition, Environment and Agriculture in the Federal Republic of Germany. Founded 40 years ago, the library developed from a document supplier on the basis of
Korwitz, Ulrich
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

AlphaFold predictions of fold-switched conformations are driven by structure memorization

Nature Communications
Recent work suggests that AlphaFold (AF)–a deep learning-based model that can accurately infer protein structure from sequence–may discern important features of folded protein energy landscapes, defined by the diversity and frequency of different ...
Devlina Chakravarty, Joseph W. Schafer, Ethan A. Chen, Joseph F. Thole, Leslie A. Ronish, Myeongsang Lee, Lauren L. Porter   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Expanding the Legacy: The National Library of Medicine Michael E. DeBakey Lecture in the History of Medicine. [PDF]

Methodist Debakey Cardiovasc J, 2022
Reznick JS, Koyle KM.
europepmc   +1 more source