Results 201 to 210 of about 6,895 (284)

Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance. [PDF]

open access: yesNat Commun
Moon K   +9 more
europepmc   +1 more source

Xanthatin Targets CISD1 to Drive Ferroptosis and Mitophagy as a Dual Anticancer Strategy in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu   +9 more
wiley   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

open access: yesAdvanced Science, EarlyView.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou   +19 more
wiley   +1 more source

Assessing semantic interoperability in environmental sciences: variety of approaches and semantic artefacts. [PDF]

open access: yesSci Data
Di Muri C   +9 more
europepmc   +1 more source

Evaporation‐Driven Solutal Marangoni Control of Rayleigh–Taylor Instability in Inverted Films

open access: yesAdvanced Science, EarlyView.
Inverted liquid films, like paint on a ceiling, are inherently unstable under gravity. This work shows that selective evaporation in volatile binary mixtures generates solutal Marangoni stresses that either suppress or amplify the Rayleigh Taylor instability.
Minwoo Choi, Hyejoon Jun, Hyoungsoo Kim
wiley   +1 more source

Systemic inequities in alcohol licensing: Case studies in eight Aotearoa New Zealand communities. [PDF]

open access: yesDrug Alcohol Rev
Randerson S   +7 more
europepmc   +1 more source

A Practical treatise on the law of nations, relative to legal effect of war on the commerce of belligerents and neutrals; and on Orders in council and licences.

open access: yesA Practical treatise on the law of nations, relative to legal effect of war on the commerce of belligerents and neutrals; and on Orders in council and licences.
identifier:https://repository.tku.ac.jp/dspace/handle/11150 ...
openaire  

Targeting WTAP/ROR1/WNT5A‐Mediated Crosstalk Between Glioma Stem Cells and Macrophages to Normalize Tumor Vasculature and Enhance Chemotherapy

open access: yesAdvanced Science, EarlyView.
In hypoxic microenvironment, WNT5A is predominantly secreted by tumor‐associated macrophages. Hypoxia‐induced WTAP mediates ROR1 stability by m6A modifications in a HuR‐dependent manner in Glioma stem cells (GSCs). WNT5A activates the WNT pathway via ROR1 binding on GSCs, driving glioma‐derived endothelial cells (GDECs) differentiation.
Xiaoyong Chen   +15 more
wiley   +1 more source

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