Results 51 to 60 of about 19,817,384 (207)

Management and environmental education in Veľká Fatra National Park (comparison with other parks of Visegrad Group)

open access: yesAnnales Universitatis Paedagogicae Cracoviensis Studia Naturae, 2016
The present study deals with the evaluation of the management of Veľká Fatra National Park and its comparison with three other selected national parks of the Visegrád Four: Bohemian Switzerland National Park (Czech Republic), Bieszczady National Park ...
Peter Repka
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Checklist of Bats in Some Areas of Azad Jammu and Kashmir

open access: yesJournal of Bioresource Management, 2018
Bats form an essential part of the ecosystem by aiding pollination, keeping insect pests in check and overall maybe helpful as indicators of health status of the ecosystem.
Fakhra Nazir   +2 more
doaj   +1 more source

Forest vegetation of the national park “Koigorodsky” (Komi republic) [PDF]

open access: yesBIO Web of Conferences
The Koygorodsky National Park was organized by the Resolution of the Government of the Russian Federation dated 07.12.2019. The area is 56.7 thousand hectares.
Kanev V.A.   +4 more
doaj   +1 more source

Areas administered by the National Park Service /

open access: yes, 1949
Vol. for 1965 includes the Registry of national landmarks.None published for 1958.Vol. for 1965 includes the Registry of national landmarks.Mode of access: Internet.Continued by: National parks & landmarks.Continues: National park system and other areas ...
United States. National Park Service.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Tourists revisit intentions based on purpose of visit and preference of the destination. A case study of Tsitsikamma National Park. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2018
Destination managers of tourist attractions need to understand the benefits of tourism and, thus, the importance of studying visitors’ intentions.
Dr T. Ramukumba
doaj  

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