Results 71 to 80 of about 563,127 (259)
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Addressing landscape conservation and community development through national park boundary
Global Ecology and ConservationIn the strategic expansion of protected areas, it is imperative to address sustainable development challenges by exploring innovative approaches to harmonize the conservation and utilization of ecological resources and landscape. Particularly, geological
Wang Qi, Zhong Linsheng, Yu Hu
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Urban National Parks or National Park Cities?
, 2018 Some of the key urban planning themes to emerge from a projectexamining uncertainties and possibilities relating to the notionof an ‘Urban National Park’ are outlined by Maggie Roe,Tim Townshend, Clive Davies, Catharine Ward Thompson,Natalie Marie Gulsrud and Qianqian ...
Roe, Maggie +4 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
A Big Battle: The State vs. Indigenous People (Case Study in Jambi Province)
JSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2019 The change in designation of Bukit Duabelas area into Bukit Duabelas National Park in Jambi province raises a conflict between the national park official who was ruling the zonation system in the national park and the Orang Rimba people who have lived ...
M. Yusuf, Syafrial Syafrial
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Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Spatial analysis of coral reefs and its degradation patterns in Bunaken National Park
E3S Web of Conferences, 2019 This article will analyze the spatial pattern as well as the degradation pattern of the coral reefs in the Bunaken National Park. Bunaken National Park is a marine national park located in the Province of North Sulawesi; the park was built as means of ...
Attamimi Nafil Rabbani, Saraswati Ratna
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