Results 91 to 100 of about 19,817,384 (207)
Spatial analysis of coral reefs and its degradation patterns in Bunaken National Park
E3S Web of Conferences, 2019 This article will analyze the spatial pattern as well as the degradation pattern of the coral reefs in the Bunaken National Park. Bunaken National Park is a marine national park located in the Province of North Sulawesi; the park was built as means of ...
Attamimi Nafil Rabbani, Saraswati Ratna
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Subscriptions received by the Appalachian National Park Association
, 2015 This 8-page report lists pledges submitted to the Parks and Forestry Committee of the Asheville Board of Trade that were turned over to the newly-formed Appalachian National Park Association.
Appalachian National Park Association;
core
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Theme Exploration and Sentiment Analysis of Online Reviews of Wuyishan National Park
LandThe study aimed to explore the relationship and interaction between humans and nature in specific areas. Latent Dirichlet allocation topic recognition and SnowNLP sentiment analysis were used to extract the topics and analyze the sentiments from visitors’
Wei Fu, Bin Zhou
doaj +1 more source
History and mission of the Appalachian National Park Association
, 2015 This 9-page history of the Appalachian National Park Association was written in April 1901, just a half year after the organization was formed. The association was formed in 1899 for the purpose of promoting the idea of a national park in the eastern U.S.
Appalachian National Park Association;
core
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Speech in support of an Appalachian National Park
, 2015 This undated, unsigned speech argues on behalf of establishing a national park east of the Mississippi. The speech could have been made at any time during the early years of the Appalachian National Park Association or at its public convention in ...
Appalachian National Park Association;
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source