Results 101 to 110 of about 19,817,384 (207)

Minutes of Meetings of the Appalachian National Park Association

open access: yes, 2015
This 248-page bound notebook contains the minutes of the meetings of the Appalachian National Park Association and the Appalachian National Forest Reserve Association.
Appalachian National Park Association; Appalachian National Forest Reserve Association
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Site for the Appalachian National Park

open access: yes, 2015
This letter to the editor, titled “Site for the Appalachian National Park,” was sent out by the Appalachian National Park Association. The written number at the top of the printed page suggests that 500 of these were printed and distributed. The focus of
Appalachian National Park Association;
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Eco-Custodians: A Contemporary Analysis of Tree Species Composition and Regeneration Health in Ramsagar and Singra National Parks, Bangladesh

open access: yesJurnal Sylva Lestari
This study systematically assessed tree species composition and regeneration status within two protected national parks in Bangladesh: Singra National Park and Ramsagar National Park. We employed a stratified random quadrat method across 100 sample plots
Md. Sahadat Hossan   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Local Wisdom vs. Modernity

open access: yesZeszyty Naukowe Wyższej Szkoły Finansów i Prawa w Bielsku-Białej
This research aims to synchronize the misalignment between local wisdom-based and contemporary management of Bunaken National Park, focusing on strengthening the rights of indigenous peoples in the Bunaken National Park area.
Riyad   +3 more
doaj   +1 more source

Legislation Secured by the Appalachian National Park Association

open access: yes, 1901
These 14 pages include several drafts of a document titled, “Legislation Secured by the Appalachian National Park Association.” The documents outline the early efforts and successes of the Appalachian National Park Association.
Appalachian National Park Association;
core  

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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