Results 121 to 130 of about 19,817,384 (207)
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
History of the Appalachian National Park Association
, 2015 These 6 pages include an overview of activities completed by the Appalachian National Park Association along with a list of persons and associations that have endorsed their work.
Appalachian National Park Association;
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Rainier National Park in the heart of the great Northwest
, 1936 Travel brochure describing the attractions and facilities at Mount Rainier National Park. Includes travel routes, rates and time schedules for railroads and the Mount Rainier Park Company auto-stages, rates for the Paradise Inn and the National Park Inn ...
Rainier National Park Company
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
PLoS ONEQuantitative evaluation of China's national park policy texts is an important window to understand its national park governance logic, top-level design of ecological protection, and future practice.
Jun-Hui Li +3 more
doaj +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Memorandum to Appalachian National Park Association membership
, 2015 This 3-page memorandum was written in September 1901 by Appalachian National Park Association president George S. Powell (b. 1848). Powell includes a summary of the association’s accomplishments to date as well as a quote by Senator Pritchard advocating ...
Powell, George S.;
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Minutes of initial meeting of the Appalachian National Park Association
, 2015 This 38-page document describes the November 22, 1899 meeting at which the Appalachian National Park Association was formed. Included in the meeting minutes is a speech by Senator Marion Butler (1863-1938), a U.S. Senator from North Carolina. The minutes
Appalachian National Park Association;
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