Results 131 to 140 of about 8,930,271 (352)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Jurnal Sylva LestariThis study systematically assessed tree species composition and regeneration status within two protected national parks in Bangladesh: Singra National Park and Ramsagar National Park. We employed a stratified random quadrat method across 100 sample plots
Md. Sahadat Hossan +3 more
doaj +1 more source
Economic Impacts of the South Denali Implementation Plan [PDF]
, 2008 This study estimates the economic effects of carrying out the South Denali Implementation Plan. The plan provides for construction of new visitor facilities in the South Denali Region.
Colt, Steve, Fay, Ginny, Szymoniak, Nick
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Profiling visitor characteristics at Tsitsikamma National Park, South Africa. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2016 South Africa has many governmental and private owned national parks and game reserves. It therefore follows that there is high level of competition amongst these national parks and game reserves in attracting tourists to visit them.
Dr. T. Ramukumba
doaj
New records for Tephritidae (Diptera) in Great Smoky Mountains National Park [PDF]
, 2000 As part of the All Taxon Biological Inventory (ATBI) being conducted in the Great Smoky Mountains National Park (GSMNP), we report new distribution and host plant records for nine Tephritidae ...
Steck, G. J., Sutton, Bruce D.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source