Results 121 to 130 of about 6,597 (209)

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Synergistic Probe Combining Lysosome Anchoring and Tumor Defense System Targeting for Precise Tumor Visualization

Advanced Science, Volume 13, Issue 44, 7 August 2026.
A new generation of high‐precision fluorescent probes based on the lysosomal characteristics in tumor metabolic reprogramming and overexpressed tumor markers. The probe (CN‐D‐GGT) selectively label cancer cells in co‐culture systems and distinguish tumor lesions from inflamedand normal tissues in vivo, enabling precise tumor imaging.
Yang Shen, Jiawei Li, Ruixi Yi, Ling Shi, Wei Li, Sulai Liu, Lin Yuan   +6 more
wiley   +1 more source

Enabling Fluoroalkyl-Sulfonylalkylation and Fluoroalkyl-Halogenation of Alkenes and Alkynes via Photoredox Catalysis. [PDF]

J Am Chem Soc
Hewa Inaththappulige SIN, Acharya A, Agampodi NDDZ, Singh H, Giri R.   +4 more
europepmc   +1 more source

Competing Pathways in Heme Catalyzed Oxidations With Porphyrin‐Centered Reactivity

ChemistryEurope, Volume 4, Issue 8, August 2026.
Heme‐catalyzed oxidations proceeding through porphyrin‐centered reactivity are quite rare. In attempts to optimize the catalytic umpolung of chloride proceeding via an isoporphyrin, we found a competing pathway. The iron(III) π‐dication readily performs alternative reactivity, leading to a bifurcation in reaction mechanisms at this point.
Silène Engbers, Lisa Wijtenhorst, Yisong Guo, Johannes E. M. N. Klein   +3 more
wiley   +1 more source

Synthesis and Preclinical Evaluation of [¹¹C]GNE-0877 as a Potential PET Radioligand for Imaging Brain Leucine-Rich Repeat Kinase 2. [PDF]

ACS Omega
Jana S, Nerella SG, Samanta SS, Liow JS, Raso IM, Montero-Santamaria JA, Zoghbi SS, Wu S, Innis RB, Telu S, Pike VW, Ding YS.   +11 more
europepmc   +1 more source

Spatial‐Scale Evolutionary Bias Sheds Light on the Latitudinal Diversity Gradient

Ecology and Evolution, Volume 16, Issue 8, August 2026.
Using Escherichia coli as a model species, our experimental findings reveal that populations in high‐fitness‐gain geographic regions undergo rapid expansion, competitively excluding populations from low‐fitness‐gain regions. This results in adaptive evolution that is biased toward areas with higher fitness potential.
Haoyuan Wu, Donghui Xu, Yonghua Wu
wiley   +1 more source

A Green, Facile Method for Selective α‑Bromination of Flavanones. [PDF]

ACS Omega
Sigmon AJ, Laremore TN, Yennawar H, Guerin GC, Pelletier B, Dallal S, Aggroia S, Englert M, George C.   +8 more
europepmc   +1 more source

4‐FPAC‐Modulated Tumor‐Associated Macrophage Conditioned Media Suppresses Malignant Phenotypes and Promotes Cell‐Cycle Arrest and Apoptosis in NSCLC

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
4‐FPAC‐modulated TAM conditioned media attenuated proliferation, EMT, angiogenesis, and stemness while inducing cell‐cycle arrest and apoptosis in NSCLC cells. These anti‐tumor effects were associated with disruption of the IL8–CD163 axis, supporting the potential of 4‐FPAC as a tumor microenvironment‐targeted therapeutic agent. ABSTRACT Non‐small cell
Anjali Singh, Dhanush Danes, Suresh Balakrishnan   +2 more
wiley   +1 more source

<i>Atractylodes macrocephala</i> Koidzumi modulates human colonic motility via ICCs pacemaker suppression and cAMP/ATP-sensitive K⁺ channel pathways. [PDF]

Int J Med Sci
Sung TS, Ko SJ, Choi WG, Park JW, Kim BJ.   +4 more
europepmc   +1 more source

Structure‐Controlled Cyclopentadithiophene Derived Non‐Fullerene Acceptors for Efficient Near‐Infrared Organic Photodetectors

Small, Volume 22, Issue 43, 3 August 2026.
This work demonstrates high‐performance solution‐processed NIR OPDs using DTP‐ and DTTP‐based NFAs (OC and SC), where donor‐core engineering enables tunable absorption and balanced optoelectronic properties; notably, DTP‐based devices achieve broad NIR response, low dark current, and high detectivity, highlighting their potential for advanced NIR ...
Jong‐Woon Ha, Jae‐Hyun Kim, Byoungwook Park, Honghyun Park, Sung Cheol Yoon, Jaebin Jeong, Seunghun Lee, Jaeil Park, Jun‐Gyu Choi, Seo‐Jin Ko, Seung‐Hoon Lee, Sungjun Park   +11 more
wiley   +1 more source