Results 141 to 150 of about 6,597 (209)

The GSK3/SHAGGY‐like OsGSK3 phosphorylates and inhibits phase separation of OsFCA at Ser‐43 and Ser‐45 to regulate brassinosteroid signaling and rice architecture

open access: yesNew Phytologist, Volume 251, Issue 4, Page 1909-1929, August 2026.
A working model for GLYCOGEN SYNTHASE KINASE 3‐mediated phosphorylation of FLOWERING CONTROL LOCUS A in the regulation of brassinosteroid signaling and rice growth and development. Summary Brassinosteroid (BR) signaling plays a critical role in rice (Oryza sativa L.) grain development.
Jiaqi Zhang   +14 more
wiley   +1 more source

Mechanochemistry Meets Catalysis: Metal Complexes for Greener Organic Transformations

open access: yesAngewandte Chemie, Volume 138, Issue 29, 13 July 2026.
Mechanochemistry is redefining metal catalysis by controlling catalyst formulation, speciation, and deployment. This Review shows how milling, LAG, RAM, and TSE enable rapid metal‐complex assembly, distinctive catalytic manifolds, and scalable synthesis beyond solution chemistry.
Sourav Behera   +2 more
wiley   +2 more sources

Advances in cryptococcal infections-associated immunopathology and potential therapeutic strategies. [PDF]

open access: yesFront Pharmacol
Sachivkina N   +6 more
europepmc   +1 more source

Designed Alleles of ZmRap2.7 Decouple the Trade‐Off Between Early Flowering and Yield Penalty

open access: yesPlant Biotechnology Journal, Volume 24, Issue 8, Page 4966-4983, August 2026.
ABSTRACT Flowering time genes often exhibit pleiotropic effects. In particular, early flowering is frequently associated with reduced grain yield due to a shorter growth period. This trade‐off poses a major challenge for developing early‐maturing and high‐yielding varieties, a key breeding objective in modern maize production. Here, we demonstrate that
Shumin Wang   +13 more
wiley   +1 more source

Identification of Pyrazolidine‐3‐One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors

open access: yesChemMedChem, Volume 21, Issue 14, 29 July 2026.
Following the discovery of oxadiazin‐5‐ones as partial inhibitors of the ATP synthase, we herein report the synthesis of a library of pyrazolidine‐3‐ones and pyrazol‐3‐ones, designed by reducing the six‐membered N–N heterocycles to five‐membered rings.
Lisa Reichert   +8 more
wiley   +1 more source

Discovery of Ligands for the TNFR1 Extracellular Domain Using Fragment‐Based Drug Discovery

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
The tumor necrosis factor receptor 1 (TNFR1) plays a major role in immunoregulation. We explored TNFR1 as a small‐molecule drug target using fragment‐based drug discovery. We found a picolinic acid fragment hit and characterized its binding mode in the extracellular domain of TNFR1.
Henri Chédotal   +6 more
wiley   +1 more source

A Solid State Zwitterionic Plastic Crystal With High Static Dielectric Constant. [PDF]

open access: yesAdv Mater
Huang Z   +7 more
europepmc   +1 more source

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