Results 151 to 160 of about 6,597 (209)

Probing 5‐Nitroimidazole‐Triazole Hybrids as Potential Anti‐Kinetoplastid Agents: Synthesis and In Vitro Efficacy

open access: yesChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of 5‐nitroimidazole‐1,2,3‐triazole hybrids was synthesised and evaluated for antitrypanosomatid activity to assess their potential as treatments against leishmaniasis and trypanosomiasis. No notable in vitro activity against Leishmania was detected.
Liandi Ferreira   +4 more
wiley   +1 more source

An Agonist/Antagonist Photo‐Switchable Vitamin D Mimetic Enables Bidirectional Optical Control of VDR

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 29, 13 July 2026.
Vitamin D exhibits complex and cell‐specific biological effects in multiple tissues via activation of the ligand‐sensing transcription factor vitamin D receptor (VDR). The photo‐switchable vitamin D mimetic 10 transitions between VDR antagonist (E) and agonist (Z) activity upon illumination and offers unprecedented bidirectional optical control over ...
Xiu Ge   +11 more
wiley   +1 more source

WWP2 ubiquitin ligase promotes colorectal cancer progression by targeting p53 for degradation: an experimental study. [PDF]

open access: yesAnn Surg Treat Res
Lee SJ   +12 more
europepmc   +1 more source

Engineering a robust IsPETase for energy-efficient PET depolymerization in natural seawater at ambient temperatures. [PDF]

open access: yesAdv Biotechnol (Singap)
Huang X   +9 more
europepmc   +1 more source

Comparison of Two DNA Labeling Dyes Commonly Used to Detect Metabolically Active Bacteria. [PDF]

open access: yesMicroorganisms
Malayil L   +4 more
europepmc   +1 more source

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