Results 71 to 80 of about 2,700,922 (312)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Project Cl@ssi 2.0. The first step towards School 2.0
Educar, 2013 The following article aims at describing the main features of the “Cl@ssi 2.0” project, which was carried out in Italy by the Ministry of Education (MIUR).
Giuseppina Cannella
doaj +1 more source
A Collaborative Pre-Practicum Apprentice Program Gives a Community College a Jump-Start in Teacher Preparation [PDF]
, 2002 The Virginia Collaborative for Excellence in the Preparation of Teachers (VCEPT), funded by a grant from the Division of Undergraduate Education of the National Science Foundation, implemented the VCEPT Pre-Practicum Apprentice Program a couple of years ...
Childers, G. F.
core +1 more source
Future career plans of Malawian medical students: a cross-sectional survey. [PDF]
, 2012 BACKGROUND: Malawi has one of the lowest physician densities in the world, at 1.1 doctors per 100,000 population. Undergraduate training of doctors at the national medical school has increased considerably in recent years with donor support.
Bartley, Tim +2 more
core +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Orphanet Journal of Rare Diseases, 2012 Background Calls have been made for governments to adopt a cohesive approach to rare diseases through the development of national plans. At present, Australia does not have a national plan for rare diseases.
Molster Caron +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
EccoS – Revista Científica, 2015 The paper presents research data that monitored the scope of the national service goal for Early Childhood Education in the State of Rio Grande do Sul, Brazil, considering the provisions of the National Education Plan 2001-2010.
Maria Luiza Rodrigues Flores +1 more
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