Results 111 to 120 of about 23,506,758 (249)
Implementing national qualifications framework policy
, 2004 This article reflects on the implementation of the National Qualifications Framework at tertiary level, using the University of South Africa as a case study and the five stated goals of the NQF as the criteria for measuring the success or otherwise of ...
Kilfoil, WR, WR Kilfoil
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
An Analysis of the Benefit of NVQ2 Qualifications Acquired at Age 26-34 [PDF]
Skills, vocational qualifications, lifelong ...
Anna Vignoles, Augustin de Coulon
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Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
ON THE CREATION OF A RESEARCH COMPETENCIES DEVELOPMENT MODEL FOR HIGHER EDUCATION PROGRAMS GRADUATES
Высшее образование в России, 2018 The article addresses one of the most urgent issues of the development of higher education in the light of the challenges of the strategy of scientific and technological development of the Russian Federation and the National system of qualifications ...
E. V. Karavaeva +2 more
doaj
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Overview of the Empirical Validation of the Strengthened Australian Qualifications Framework
, 2010 The aim of this study was to undertake an empirical analysis of the revised design of the strengthened Australian Qualifications Framework. In particular, four elements of the revised framework were to be examined: the levels structure, with 10 levels ...
Wu, Margaret +4 more
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