Results 131 to 140 of about 23,506,758 (249)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Updates to the EU Directives on Professional Qualifications must align with global standards. [PDF]

PLOS Glob Public Health
Brigante L, Af Ugglas A, Drandic D, Bent JD, Langins M, Jokinen M, Phillips K.   +6 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

National Qualifications: Health and Safety in Care - Intermediate 1

, 2012
These notes are provided to support teachers and lecturers presenting the Scottish Qualifications Authority, Health and Safety for Care Unit (F17V 10).
Scottish Qualifications Authority, Scotland's Colleges   +1 more
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Parametrisation of content of the national framework of qualifications

, 2006
Nacionalinės kvalifikacijų sąrangos šiuo metu yra kuriamos daugelyje Europos šalių. Jų poreikį lemia vykstantys ekonominiai ir technologiniai pokyčiai, intensyvėjanti konkurencija, prekių, paslaugų ir žmogiškųjų išteklių rinkų globalizacija, nacionalinės
Laužackas, Rimantas, Tūtlys, Vidmantas
core  

Mind the Gap: From Policy to Practice at CNR An Analysis of Career Advancement Criteria in Light of the Agreement on Reforming Research Assessment. [PDF]

Open Res Eur
Di Donato F, Mannocci A, Pecoraro F, Provost L.   +3 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

National Qualifications: Sociology and Psychology in Care - Intermediate 1

, 2012
These notes are provided to support teachers and lecturers presenting the Scottish Qualifications Authority F17T 10, Sociology and Psychology for Care.
Scottish Qualifications Authority, Scotland's Colleges   +1 more
core  

Pour une orientation innovante et tout au long de la vie

Revue Internationale d’Éducation de Sèvres, 2021
Federica Minichiello
doaj   +1 more source