Results 151 to 160 of about 85,743,578 (314)
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Should Research Universities be Led by Top Researchers? Part 1: Are they? [PDF]
If the best universities in the world – who have the widest choice of candidates – systematically appoint top researchers as their vice chancellors and presidents, is this one form of evidence that, on average, better researchers make better leaders ...
Amanda H Goodall
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Canada West Universities Athletic Association basketball 1997-1998 statistics
, 1998 This appears to be a page from a much larger document, most likely from the Canada West Universities Athletic Association basketball 1997-98 statistics.
Canada West Universities Athletic Association
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Australian National University Research Scholars. [PDF]
Anthropology News, 1962 openaire +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Spots of interaction: an investigation on the relationship between firms and universities in Minas Gerais, Brazil [PDF]
Spots of interaction summarize the nature of partial connections (between science and technology) operating in the Brazilian system of innovation. A pilot study in Minas Gerais, Brazil, uses two new research tools (for immature NSIs) and presents a ...
Márcia Siqueira Rapini +5 more
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From data neglect to data respect: A framework for institutionalising a sustainable research data management culture in Kenyan universities. [PDF]
PLoS OneNakitare J, Mathangani S, Kamau G.
europepmc +1 more source
A National Research Agenda and the Self-understanding of Modern Universities [PDF]
, 2017 Claassen, R.J.G., Düwell, M.
openaire +3 more sources