Results 221 to 230 of about 85,743,578 (314)

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Where, when, how, and with whom do young university students engage in physical activity? A cluster-derived spectrum of patterns across 16 European universities. [PDF]

PLoS One
Llena C, Fermon L, Andkjær S, Aulanier A, Berrigan F, Bortoletto N, Costa MJ, Delevoye-Turrell Y, Derigny T, Dieu O, Garcin M, Gandrieau J, Fernandes RJ, Flemr L, Fullerton C, Hong HJ, Huchez A, Joing I, Lentillon-Kaestner V, Mauger A, Mazza B, Mekkaoui L, Michelini E, Michelsen la Cour A, Mouton A, Nosal P, Olivares PR, Olstad BH, Rejman M, Soares S, Vilas-Boas JP, Vogt T, Porrovecchio A, Potdevin F.   +33 more
europepmc   +1 more source

1pID8 - Acoustic Research at the National University of Singapore

, 2021
openaire   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Light meal consumption among university students in China: A multi-regional cross-sectional study of behavioral patterns, influencing factors, and service optimization strategies under supply-side heterogeneity. [PDF]

PLoS One
Zhang H, Zhou B, Wang J, Li Y.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Estimating the Effect of Physical Education Reform on College Students' Mental Health with Difference-in-Differences. [PDF]

Behav Sci (Basel)
Ma Z, Zhu R, Madiyeva G, Bulatbayeva A.
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Comprehensive Analysis of the Global Standing of Universities, Research Performance, and the Impact of Scholarly Journals: Pakistan's Academic and Research Landscape 2026. [PDF]

Pak J Med Sci
Meo SA, Khan A, Jawaid SA.
europepmc   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source