Results 91 to 100 of about 334,738 (212)
FROM CRAFT SCHOOL TO NATIONAL RESEARCH UNIVERSITY OF TECHNIQUE AND TECHNOLOGY
The article highlights the features of engineering training at engineering training, the specific character of so call «Russian method» of engineers’ training.
Anatoliy A. Aleksandrov
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Expert Consensus on Standardized Practice of Oral Contrast Agent-Enhanced Gastric Ultrasonography (Shanghai, 2020 edition) [PDF]
Gastrointestinal Ultrasound Task Force, Ultrasound Research and Education Institute, Clinical Research Center of Interventional Medicine, School of Medicine, Tongji University , Shanghai Engineering Research Center of Ultrasound Diagnosis and Treatment , National Clinical Research Center of Interventional Medicine , Abdominal Group, Ultrasound Branch, Shanghai Medical Association , Abdominal and Vascular Ultrasound Sub-Committee, Society of Ultrasound Medicine, Shanghai Association of Social Medical Institutions
doaj +1 more source
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
FULFILLING INNOVATIVE POTENTIAL IS A PRIORITY FOR BELGOROD STATE NATIONAL RESEARCH UNIVERSITY
The article considers the dynamics of the research and innovation potential of Belgorod State National Research University (BelSU) in recent years and the main achievements of the University in research and innovation; it also looks at the experience ...
Igor S. Konstantinov +2 more
doaj
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source

