Results 91 to 100 of about 47,913,155 (276)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
National Science Foundation: Science Nation
Billed as "The Online Magazine That's All About Science for the People", the online magazine Science Nation reports on important science breakthroughs.
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Eos, Transactions American Geophysical Union, 1994 Considering the current budget crunch, NSF will see a large increase in fiscal year 1995. Its budget request is $3.2 billion, an increase of 6% over the 1994 level of $3.0 billion. The increase reflects the administration's emphasis on science and technology.This total includes $2.3 billion for Research and Related Activities, an increase of 8.3% over ...
openaire +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Progress in exosome-related research supported by the National Natural Science Foundation of China
Fundamental ResearchExosomes are characterized as extracellular vesicles (EVs) ranging from 30-150 nm in diameter that widely exist in body fluids, tissues and organs and are important intercellular communicators.
Yuanyi Wang +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
National Science Foundation: Current
Current, is a newsletter published monthly by the National Science Foundation (NSF) and the scope of each newsletter is to highlight the research and education that is supported by NSF.
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What does Congress want from the National Science Foundation? A content analysis of remarks from 1995 to 2018. [PDF]
Sci Adv, 2020 Lupia A, Soroka S, Beatty A.
europepmc +1 more source