Results 191 to 200 of about 47,913,155 (276)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

National Science Foundation

, 1974
National Science Foundation
core   +1 more source

Enhancing Quasi-Two-Dimensional Electronic Structure in Bi₂O₂Se via Chlorine Substitution. [PDF]

Adv Sci (Weinh)
Jiang YZ, Wen QX, Xu X, Sun ST, Ren FF, Zhou ZX, You XY, Kan YC, Zhang Z, Liu JY, Zhao YZ, Liu ZT, Ye M, Yao SH, Zhou J, Chen YB, Liu ZK, Chen YL, Lv YY, Chen C.   +19 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

National Science Foundation

, 1975
National Science Foundation
core   +1 more source

A Li metal-SiO<i>_x</i> hybrid anode enabling synergistic plating/alloying dual-mechanism lithium storage. [PDF]

Sci Adv
Zhang CH, Zhang J, Wang YH, Tan SJ, Guo YJ, Guo JC, Luo XX, Wu JS, Xin S, Wan LJ, Guo YG.   +10 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Correction: Mechanical properties of the tumor microenvironment: drivers of immunotherapy resistance in solid tumors. [PDF]

Front Immunol
Zhang Z, Deng T, Zhou W, Tan X.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

The 100 Diatom Genomes Project. [PDF]

PLoS Biol
Mock T, Bilcke G, Flaum E, Fu S, Hoch L, Moog K, Rijsdijk N, Ruck EC, Bishop IW, Duchene C, Gilbertson R, Hopes A, Johns C, Manfellotto F, Roberts WR, Belshaw N, Chandola U, Chaerle P, Chepurnova O, Deleu D, D'hondt S, Di Costanzo F, Dudin O, Flori S, Gaikwad T, Groisillier A, Hall A, Ji P, Lavier-Aydat LJ, Lewis WH, Menicot S, Pinseel E, Pottier E, Sarkozi K, Smerilli A, Strauss J, Thierens S, Toseland A, Touhami Y, Utting R, Van Bel M, van Oosterhout C, Wu Y, Yang F, Allhusen E, Bolton JJ, Bowler C, Brinkhoff T, Poehlein A, Brovarone T, Chen N, Clark G, Clark MD, Copetti D, Cui Z, Deng B, Jian J, John U, Jungblut AD, Kang J, Kristoffersen JB, Lee J, Liu S, Mann DG, Medlin L, Moulton V, Radojicic J, Sato S, Trobajo R, Wolf K, Yamada N, Ye N, Zhang L, Zhuang Y, Dey G, Di Dato V, Helliwell K, Jaubert M, Kroth PG, Montresor M, Romano G, Rynearson TA, Talag J, Valentin KU, Vincent F, Waller RF, Wheeler G, Alverson AJ, Barry K, Boston L, Falciatore A, Ferrante MI, Guo J, Grimwood J, Hayes R, Herdean A, Jenkins J, Kim M, Kooistra WH, Kuo A, Lipzen A, Poulsen N, Schmutz J, Tirichine L, Vandepoele K, Verret F, Vyverman W, Grigoriev IV.   +107 more
europepmc   +1 more source