Results 41 to 50 of about 133,024 (255)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Predictors of surgical site infection following reconstructive flap surgery: A multi-institutional analysis of 37,177 patients

Frontiers in Surgery, 2023
PurposeRates of surgical site infection (SSI) following reconstructive flap surgeries (RFS) vary according to flap recipient site, potentially leading to flap failure.
Bashar Hassan, Abdulghani Abou Koura, Adham Makarem, Kamal Abi Mosleh, Hani Dimassi, Hani Tamim, Hani Tamim, Amir Ibrahim   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Overview of Key Technologies in Surgical Robots and Optimization Discussions

Zhongguo yiliao qixie zazhi
Surgical robot is the national strategic diagnostic and therapeutic equipment research focus, get a number of scientific research institutes, colleges and universities and enterprises pay extensive attention to the design and development of a variety of ...
Xunjun MA, Jun YU, Haitao LIU, Ya LI, Hao WU, Yanbo HUANG, Bide XU, Li LIN, Jinwu WANG   +8 more
doaj   +1 more source

The feasibility of virtual reality for anatomic training during temporal bone dissection course

Frontiers in Virtual Reality, 2022
Introduction: In recent decades, the lack of educational resources for cadaveric dissections has complicated the hands-on otological surgical training of otorhinolaryngology residents due to the poor availability of cadaver temporal bones, facilities ...
Tomi Timonen, Tomi Timonen, Matti Iso-Mustajärvi, Matti Iso-Mustajärvi, Pia Linder, Hana Vrzakova, Saku T. Sinkkonen, Saku T. Sinkkonen, Veera Luukkainen, Veera Luukkainen, Jaakko Laitakari, Antti-Pekka Elomaa, Antti-Pekka Elomaa, Aarno Dietz   +13 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Comparison of time and cost between conventional surgical planning and virtual surgical planning in orthognathic surgery in Korea

Maxillofacial Plastic and Reconstructive Surgery, 2019
Background The purpose of this study was to measure the time of the conventional surgical planning (CSP) and virtual surgical planning (VSP) in orthognathic surgery and to compare them in terms of cost.
Si-Yeon Park, Dae-Seok Hwang, Jae-Min Song, Uk-Kyu Kim   +3 more
doaj   +1 more source

High-power short-duration vs. standard radiofrequency cardiac ablation: comparative study based on an in-silico model

International Journal of Hyperthermia, 2021
Purpose While the standard setting during radiofrequency catheter ablation (RFCA) consists of applying low power for long times, a new setting based on high power and short duration (HPSD) has recently been suggested as safer and more effective.
Sergi Coderch-Navarro, Enrique Berjano, Oscar Camara, Ana González-Suárez   +3 more
doaj   +1 more source

Increasing socioeconomically disadvantaged patients’ engagement in breast cancer surgery decision-making through a shared decision-making intervention (A231701CD): protocol for a cluster randomised clinical trial

BMJ Open, 2022
Introduction Socioeconomic disparities for breast cancer surgical care exist. Although the aetiology of the observed socioeconomic disparities is likely multifactorial, patient engagement during the surgical consult is critical.
John Taylor, David Zahrieh, Paul J Rathouz, Jennifer L Tucholka, Jessica R Schumacher, Bret M Hanlon, Selina Chow, Rachel Wills, Heather B Neuman   +8 more
doaj   +1 more source