Results 51 to 60 of about 75,706 (263)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Towards the issue of American national identity (political and ideological factors of its establishing)

open access: yesStudia Humanitatis, 2013
In the article the author considers the key political and ideological factors of American national identity establishing, analyzing the main distinguishing features of American national character formation.
Bureiko Nadiya Mykolaivna
doaj  

Menguatkan Kembali Nilai Multikulturalisme dan Persatuan Bangsa Melalui Pembelajaran Sejarah

open access: yesDiakronika, 2019
This article is motivated by the heat of the conditions of the Indonesian people at this time which was started by reporting the chaos between supporters of soccer that caused casualties, then the heat of political elections in 2019 which caused a split
Mohamad Ully Purwasatria
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Capital city relocation in Indonesia: compromise failure and potential dysfunction

open access: yesCogent Social Sciences
The relocation of Indonesia’s capital city from Jakarta to Nusantara in East Kalimantan, as proposed by President Joko Widodo, represents a profound shift in the nation’s urban and political geography.
Indra Perwira   +3 more
doaj   +1 more source

Official congratulations on National Unity Day: Genre and pragmatic features [PDF]

open access: yesЖанры речи
The article deals with the problem of the genre originality of official congratulations on National Unity Day. The research is based on official congratulations on National Unity Day, posted on the official accounts of government bodies and officials on ...
Gromyko, Sergey Aleksandrovich
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Summary

open access: yesУкраїнське Pелігієзнавство, 1998
In the Section "Religious Problems in the Ukraine" there are published the papers by A.N.Kolodny "National Churches in the contex of national renascence of the Ukraine", E.K.Duluman  "Religion in the Fortune of the Ukrainian people (historical Past and ...
Editorial board of the Journal
doaj   +1 more source

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