Results 31 to 40 of about 13,079,187 (265)
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Native American Science Outreach Network Resource Guide [PDF]
By the spring of 1994. the Outreach Programs of the UW Department of Chemistry resembled the proverbial elephant as described by three blind people.
Native American Science Outreach Network
core +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Abstracts and Notes on Contributors
s and notes on Contributors of the feature texts in RIAS Vol. 12, Spring–Summer № 1 /2019.
RIAS Editors
doaj +1 more source
The Alaska Native Tumour Registry: fifty years of cancer surveillance data for Alaska Native people
Like other Indigenous Circumpolar populations, Alaska Native (AN) people experience different patterns of cancer than their non-Indigenous counterparts.
Sarah H Nash +4 more
doaj +1 more source
Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran +13 more
wiley +1 more source
Previous research has shown that Appalachian Studies as a field, by drawing upon Appalachian Studies scholars and activists such as Harry Caudill, Helen Lewis, and Chris Irwin, misapplied the colonialism model to whites in the region, which resulted in ...
Jason Hockaday
doaj +1 more source
Indigenous screendance challenges US settler colonial constructions that drive political, environmental, and global injustices, which the Covid-19 pandemic has exacerbated.
Kate Mattingly, Tria Blu Wakpa
doaj +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Bi‐ and Mono‐Allelic RFC1 Expansion in a North American Cohort With Idiopathic Axonal Neuropathy
ABSTRACT Objective RFC1 biallelic repeat expansion is increasingly recognized as a cause of chronic idiopathic axonal polyneuropathy (CIAP), but it remains challenging to know who to test. This study aims to determine the prevalence of biallelic and monoallelic RFC1 expansions and their corresponding neuropathy phenotypes in CIAP patients and identify ...
Amro M. Stino +25 more
wiley +1 more source

