Results 41 to 50 of about 387,629 (259)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Social networks of American Indian youth on a Northern Plains reservation

Connections
Social relations and multigenerational networks remain a salient fixture of American Indian (AI) culture and survivance. Network data can describe the dynamic nature of social networks and the powerful role these relationships play in the development of ...
Schultz Katie, Ivanich Jerreed, Whitesell Nancy, Siciliano Michael, Zacher Tracy   +4 more
doaj   +1 more source

Adult outcomes of childhood bronchiectasis

International Journal of Circumpolar Health, 2020
Recent literature has highlighted the importance of transition from paediatric to adult care for children with chronic conditions. Non-cystic fibrosis bronchiectasis is an important cause of respiratory morbidity in low-income countries and in indigenous
Dawn Sibanda, Rosalyn Singleton, John Clark, Christine Desnoyers, Ellen Hodges, Gretchen Day, Gregory Redding   +6 more
doaj   +1 more source

Association Between Motor Pathway Damage and Motor Deficit in Upper and Lower Limb in People With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corticospinal tract damage is common in people with MS, but the degree of clinical symptoms varies. We hypothesize that corticospinal tract lesions are more extensive and severe in people with MS with motor impairments in both upper and lower limbs.
Mathilde Liffran, Malo Gaubert, Alice Dufey, Elise Bannier, Audrey Rico, Jean‐Christophe Ferré, Raphaël Chouteau, Laure Michel, Emmanuelle Le Page, Virginie Callot, Bertrand Audoin, Sarah Demortière, Benoît Combès, Anne Kerbrat   +13 more
wiley   +1 more source

Native American Tribes and dam removal: Restoring the Ottaway, Penobscot, and Elwha rivers

Water Alternatives, 2022
Since the early 1900s, more than 1700 dams have been removed from rivers in the United States. Native American Tribes have played a key role in many significant removals, bringing cultural, economic, and legal resources to bear on the process.
Coleen A. Fox, Nicholas J. Reo, Brett Fessell, Frank Dituri   +3 more
doaj  

Efficacy of Inebilizumab in N‐MOmentum Trial Participants With or Without Prior Immunosuppressants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This post hoc analysis examined the impact of prior immunosuppressants on the long‐term efficacy and safety of inebilizumab, a cluster of differentiation 19+ B‐cell–depleting monoclonal antibody, in participants with aquaporin‐4–seropositive neuromyelitis optica spectrum disorder from the N‐MOmentum trial (NTC02200770).
Bruce A. C. Cree, Beatrice Suero, Sarah Walsh, Romain Marignier, John W. Lindsey, Ho Jin Kim, Dewei She, Daniel Cimbora, Dustin Cavida, Friedemann Paul   +9 more
wiley   +1 more source

Police Stops and Searches of Indigenous People in Minneapolis: The Roles of Race, Place, and Gender

International Indigenous Policy Journal, 2019
We examine disparities in police stops, searches, and arrests of Native Americans in Minneapolis, a major metropolitan area with a substantial Native American population.
Marina M. Gorsuch, Deborah T. Rho
doaj   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Discourse on Indigenous-police interactions

Humanities & Social Sciences Communications
A long tumultuous history between Indigenous Peoples and police continues to negatively impact Indigenous Peoples in the criminal justice system to this day. In collaboration with the Portland Committee on Community-Engaged Policing, the current research
Catherine Cheung, Adam Thomas Murry, Theodore Latta, Michael Alex Bednar, Zahra Premji, K. Alix Hayden   +5 more
doaj   +1 more source

Gaps and opportunities for measuring equity with the Translational Science Benefits Model: Recommendations from the Center for American Indian and Alaska Native Diabetes Translation Research

Journal of Clinical and Translational Science
Translational research needs to show value through impact on measures that matter to the public, including health and societal benefits. To this end, the Translational Science Benefits Model (TSBM) identified four categories of impact: Clinical ...
Amy G. Huebschmann, Angela G. Brega, Sarah A. Stotz, Aliassa L. Shane, Roxanna King, Valarie Blue Bird Jernigan, Kaylee R. Clyma, R. Turner Goins, Gary L. Ferguson, Tassy Parker, Nathania Tsosie, Sara J. Mumby, Spero M. Manson, Meredith P. Fort   +13 more
doaj   +1 more source