Results 21 to 30 of about 345,729 (263)
"A Very Old Problem": Uncovering Networks of (Mis)Communication in Early America
Southern Spaces, 2017 Nathaniel F. Holly reviews Alejandra Dubcovsky's Informed Power: Communication in the Early American South (Boston, MA: Harvard University Press, 2016).
Nathaniel F. Holly
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Nascent Nations: A Review of Chiefdoms, Collapse, and Coalescence in the Early American South
Southern Spaces, 2015 Garrett Wright reviews Robin Beck's Chiefdoms, Collapse, and Coalescence in the Early American South (Cambridge: Cambridge University Press, 2013).
Garrett Wright
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Indigenous Virginia Digital Storytelling Project: A Creation Story
Genealogy, 2021 Indigenous ways of knowing and being are invested in creating and maintaining relationships, respectful and equitable exchange, and collective but particularistic knowledges that are practical, useful, and helpful in extending meaning-making within ...
Kasey Jernigan, Beth Roach
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RSA Journal, 1994 This essay, which is part of a work in progress on the subject, outlines the various views on Native Americans held by Italian explorers, missionaries, travelers, anthropologists, and writers in the past four centuries.
Fedora Giordano
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Hearing the Call: The Cultural and Spiritual Journey of Rosemary McCombs Maxey
Southern Spaces, 2018 In this documentary video, Craig Womack and Steve Bransford explore the continuance of the Creek language, spoken by tribal people in Oklahoma and Florida, by centering upon the life of the Creek community leader, feminist, and activist, Rosemary McCombs
Craig Womack, Steve Bransford
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Ethnic Cleansing and the Trail of Tears: Cherokee Pasts, Places, and Identities
Southern Spaces, 2017 James Taylor Carson reviews Gregory D. Smithers's The Cherokee Diaspora: An Indigenous History of Migration, Resettlement, and Identity (New Haven: Yale University Press, 2015).
James Taylor Carson
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source