Results 111 to 120 of about 33,583 (261)

Liraglutide combined with dapagliflozin treatment improves myocardial disease and endothelial dysfunction in T2DM mice

open access: yesJournal of Diabetes Investigation, EarlyView.
Liraglutide combined with Dapagliflozin treatment improves myocardial disease and endothelial dysfunction in T2DM mice. Diabetic cardiomyopathy (DCM) and endothelial dysfunction were established in mice via HFD and STZ injection. The combination therapy of Liraglutide and Dapagliflozin synergistically improved metabolic parameters and attenuated ...
An‐Jun Tan   +5 more
wiley   +1 more source

The prevalence of frailty and associated factors in patients with type 2 diabetes mellitus and coronary heart disease: A cross‐sectional study

open access: yesJournal of Diabetes Investigation, EarlyView.
Among 217 participants, 43.8% were frail. Frailty was common among patients with T2DM and CHD. Blood glucose, BNP, anxiety, sleep duration, nutritional risk, history of PCI, and age were independently associated with frailty in patients with T2DM and CHD.
Junwen Ma, Jing Wang, Wei Zhu
wiley   +1 more source

Comparison between liraglutide and dulaglutide on the incidence or progression of eye and kidney complications

open access: yesJournal of Diabetes Investigation, EarlyView.
We conducted the single‐center, retrospective cohort study to evaluate and compare the risk of diabetic eye and kidney complications between newly initiated once‐daily liraglutide (0.9 mg) and once‐weekly dulaglutide (0.75 mg) in 331 Japanese patients with type 2 diabetes.
Aki Katamine   +4 more
wiley   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

open access: yesJournal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li   +6 more
wiley   +1 more source

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti   +11 more
wiley   +1 more source

NT‐proBNP as a Predictor of Atrial Fibrillation Recurrence After Cryoballoon, Radiofrequency and Pulsed‐Field Ablation

open access: yesPacing and Clinical Electrophysiology, EarlyView.
Central Illustration: In a study investigating AF recurrence after PVI with RFA, CBA, and PFA, elevated NT‐proBNP emerged as a strong predictor of recurrence within the first year, outperforming other clinical measures. Color‐coded recurrence‐free survival probability charts derived from these data are proposed to support individualized clinical ...
Johannes Bruss   +11 more
wiley   +1 more source

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs   +13 more
wiley   +1 more source

Septic Shock and Prognosis in Dogs and Cats With Sepsis—Consensus Definition and Clinical Criteria

open access: yesJournal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Death from sepsis results from progressive organ dysfunction. Early recognition of increased illness severity or deterioration in clinical status enables timely interventions that can improve outcomes. We aimed to define septic shock by consensus and to use the existing literature to identify associated clinical and clinicopathologic ...
Robert Goggs   +13 more
wiley   +1 more source

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