Results 141 to 150 of about 105,476 (242)

Association of neutrophil-to-lymphocyte ratio (NLR) with the infarct size in acute myocardial infarction (AMI), through peak creatine kinase (CK) and peak creatine kinase-myocardial band (CK-MB): A retrospective observational study. [PDF]

Medicine (Baltimore)
Shirasaki K, Minai K, Ogawa K, Nagoshi T, Ogawa T, Kawai M, Tokuda M, Yoshimura M.   +7 more
europepmc   +1 more source

Sacubitril/Valsartan Attenuates Inflammation and Fibrosis Associated With Decreased Integrin α8 and Inhibits Hepatocarcinogenesis in a Rat Model of Metabolic Dysfunction‐Associated Steatohepatitis

Hepatology Research, EarlyView.
Sacubitril/Valsartan (Sac/Val) alleviates fibrosis and inflammation in metabolic dysfunction‐associated steatohepatitis (MASH). Its anti‐fibrotic effect is linked to the suppression of Integrin alpha 8 (Itga8), a protein crucial for hepatic stellate cell (HSC) activation and collagen production.
Hayato Kawamura, Aya Naiki‐Ito, Xiaochen Kuang, Akihiro Murakami, Masayuki Komura, Takanori Suzuki, Hiroyuki Kato, Yuko Nagayasu, Kentaro Matsuura, Kei Fujiwara, Hiromi Kataoka, Satoru Takahashi   +11 more
wiley   +1 more source

Functional analysis of NPR2 variants supports the therapeutic rationale for CNP in short stature. [PDF]

Am J Hum Genet
Jeong R, Covarrubias S, Shanghavi D, Ruhrmund D, Estrada K, Zhou D, Marom N, Bauer CR, Froelich S.   +8 more
europepmc   +1 more source

Pathogenesis and Therapeutics for Chronic Pruritus of Unknown Origin: A Systematic Review

International Journal of Dermatology, EarlyView.
ABSTRACT Chronic pruritus of unknown origin (CPUO) is a distressing condition characterized by persistent itch lasting over 6 weeks without an identifiable cause. The underlying mechanisms remain poorly understood, complicating diagnosis and treatment.
Yagiz Matthew Akiska, Isha Gandhi, Robert Adler, Deena Fayyad, Perya Bhagchandani, Shabnam Afzal, Waleed Adawi, Shivani Patel, Shawn G. Kwatra   +8 more
wiley   +1 more source

Breast cancer susceptibility gene 2 upregulation alleviated cardiac hypertrophy in angiotensin II-treated mice. [PDF]

Biochem Biophys Rep
Liu K, Gong XX, Li Y, Li MZ, Si C, Zhou L.   +5 more
europepmc   +1 more source

Cost‐Utility Analysis of Left Bundle Branch Area Versus Biventricular Pacing for Cardiac Resynchronization Therapy: A Multicenter, Prospective, Quasi‐Experimental Study

Journal of Cardiovascular Electrophysiology, EarlyView.
Cost‐utility of LBBAP CRT versus BVP CRT. ABSTRACT Introduction Cardiac resynchronization therapy (CRT) is a well‐established treatment for patients with heart failure (HF). Recently, left bundle branch area pacing (LBBAP) has emerged as a more physiological alternative to biventricular pacing (BVP) for CRT.
José M. Sánchez‐Moreno, Leticia García‐Mochón, Manuel Molina‐Lerma, Guillermo Gutiérrez‐Ballesteros, Manuel Frutos‐López, Ricardo Pavón‐Jiménez, M. C. Olvera‐Porcel, Juan Jiménez‐Jáimez, Miguel Álvarez   +8 more
wiley   +1 more source

Association of NT-proBNP and sST2 with Diastolic Dysfunction in Cirrhotic Patients and Its Therapeutic Implications. [PDF]

Int J Mol Sci
Chiorescu RM, Ruda A, Chira R, Nagy G, Bințințan A, Chiorescu Ș, Mocan M.   +6 more
europepmc   +1 more source

Cardiometabolic‐Inflammatory Risk Factors and Cognitive Decline Among Older Indians—Report From a Nationally Representative, Longitudinal Study

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Rapid increase in cardiometabolic diseases in India may contribute to increased incidence of late‐life cognitive impairment. This study focuses on associations between baseline cardiometabolic risk factors and subsequent decline in cognitive function among older adults in India, leveraging data from two waves (Wave 1: 2017–2020 ...
Joyita Banerjee, Jung Ki Kim, Emma Nichols, Pranali Khobragade, A. B. Dey, Sharmistha Dey, Eileen Crimmins, David Flood, Kenneth M. Langa, Jinkook Lee, Peifeng Hu   +10 more
wiley   +1 more source

B-Type Natriuretic Peptide as a Marker of Subclinical Heart Disease in a High-Burden Emergency Department Population With Sustained Asymptomatic Hypertension. [PDF]

Int J Hypertens
Souffront K, Nelson BP, Lukas M, Garay HR, Shubeck C, Gordon L, Loo GT, Degtyar A, Wilder M, Iddrisu H, Coleman B, Richardson LD.   +11 more
europepmc   +1 more source

The urinary albumin‐to‐creatinine ratio can direct personalized prevention and treatment for cardiovascular and chronic kidney disease

Journal of Internal Medicine, EarlyView.
Abstract Increased urinary albumin excretion is a strong predictor for cardiovascular events in persons with and without decreased glomerular filtration rate and can be assessed with the urinary albumin‐to‐creatinine ratio (UACR), which is a selective, sensitive, and convenient method for patients.
Holly J. Kramer, George L. Bakris
wiley   +1 more source