Results 91 to 100 of about 990,536 (371)

The role of natriuretic peptides in volume assessment and mortality prediction in Haemodialysis patients

BMC Nephrology, 2015
BackgroundMaintaining optimal fluid balance is essential in haemodialysis (HD) patients but clinical evaluation remains problematic. Other technologies such as bioimpedance are emerging as valuable adjuncts.
M. Sivalingam, E. Vilar, S. Mathavakkannan, K. Farrington   +3 more
semanticscholar   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

Annals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek, David F. Hanff, Pim J. French, Sarah A. van Dijk, Erik A.C. Wiemer, Olivier C. Manintveld, Martin J. van den Bent, Walter Taal   +7 more
wiley   +1 more source

Type of atrial fibrillation and clinical outcomes in patients with heart failure and reduced ejection fraction [PDF]

, 2017
Background: Atrial fibrillation (AF) is common in heart failure (HF), but the outcome by type of AF is largely unknown. Objectives: This study investigated outcomes related to type of AF (paroxysmal, persistent or permanent, or new onset) in 2 ...
Abraham, William T., Desai, Akshay S., Dickstein, Kenneth, Jhund, Pardeep S., Køber, Lars, McMurray, John J.V., Mogensen, Ulrik M., Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R.   +11 more
core   +3 more sources

Natriuretic peptides for the detection of paroxysmal atrial fibrillation

Open Heart, 2015
Background and purpose Silent atrial fibrillation (AF) and tachycardia (AT) are considered precursors of ischaemic stroke. Therefore, detection of paroxysmal atrial rhythm disorders is highly relevant, but is clinically challenging.
J. Seegers, Markus Zabel, Timo Grüter, A. Ammermann, M. Weber-Krüger, F. Edelmann, G. Gelbrich, Lutz Binder, C. Herrmann-Lingen, K. Gröschel, G. Hasenfuss, Nicolas Feltgen, B. Pieske, R. Wachter   +13 more
semanticscholar   +1 more source

Case‐Based Immunology: B Cells and Systemic Sclerosis Interstitial Lung Disease

Arthritis &Rheumatology, EarlyView.
Interstitial lung disease (ILD) is an important complication of systemic sclerosis (SSc), with high mortality and morbidity. Recent clinical studies in SSc‐ILD have led to US Food and Drug Administration–approved therapies in SSc‐ILD. Importantly, evidence from these studies has been extrapolated to guide management of ILDs of other systemic autoimmune
Nina Goldman, Voon Ong, Christopher P. Denton   +2 more
wiley   +1 more source

Role of the liver in splanchnic extraction of atrial natriuretic factor in the rat [PDF]

, 1992
Mesenteric, hepatic and splanchnic extraction of C-terminal and N-terminal atrial natriuretic factor was investigated in male Sprague-Dawley rats. Plasma concentrations (mean ± S.E.M.) of C-terminal atrial natriuretic factor were 55.0 ± 6.1 fmol/ml, 31.2
Alexander L. Gerbes, Arendt, Casado, Crozier, De Bold, Dieter Jüngst, Epstein, Gaétan Thibault, Gerbes, Gerbes, Gerbes, Gerbes, Gerbes, Gines, Gutkowska, Henriksen, Henriksen, Hollister, Inagami, Johnson, Krieter, Krieter, Kurusawa, Lang, Laragh, Manfred Bilzer, Masuda, Moreau, Nair, Needleman, Rochus Witthaut, Schütten, Sundsfjord, Tamburini, Thibault, Veit Gülberg, Veseley, Vierhapper, Vollmar, Widimsky   +39 more
core   +1 more source

Long‐Term Outcomes of Reduced Intensity Conditioning Hematopoietic Stem Cell Transplantation for Systemic Sclerosis Patients with Impaired Cardiac Function

Arthritis &Rheumatology, Accepted Article.
Objective High intensity conditioning autologous hematopoietic stem cell transplantation (AHSCT) is standard of care for patients with advanced SSc. The role of reduced intensity conditioning (RIC) prior to AHSCT in this population remains unclear. We conducted this study to determine the long‐term outcomes of RIC AHSCT in SSc patients with cardiac ...
Yonatan Lean, Carrie Richardson, Anthony Esposito, Katy Bedjeti, George E. Georges   +4 more
wiley   +1 more source

Cardiovascular natriuretic peptides in emergency

Emergency Care Journal, 2005
Natriuretic peptides have emerged as important candidates for development of diagnostic tools in cardiovascular disease being the establishment of the cause of shortness of breath in the acute setting (Emergency Department) one of most interesting ...
Martina Zaninotto, Monica Mion, Stefano Rocco, Mario Plebani   +3 more
doaj   +1 more source

Cell surface protein disulfide isomerase regulates natriuretic peptide generation of cyclic guanosine monophosphate. [PDF]

PLoS ONE, 2014
The family of natriuretic peptides (NPs), including atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), exert important and diverse actions for cardiovascular and renal homeostasis.
Shuchong Pan, Horng H Chen, Cristina Correia, Haiming Dai, Tyra A Witt, Laurel S Kleppe, John C Burnett, Robert D Simari   +7 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source