Results 151 to 160 of about 25,222 (258)

Exploring the association of natriuretic peptides with QTc interval in hemodialysis patients. [PDF]

Ren Fail
Matsumoto Y, Mori Y, Kageyama S, Yoshimura K, Saito T, Terada R, Nojima Y.   +6 more
europepmc   +1 more source

Timing and duration of glucagon‐like peptide‐1 receptor agonist use and risk of nonarteritic anterior ischaemic optic neuropathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To investigate the association between glucagon‐like peptide‐1 receptor agonist (GLP‐1RA) use and nonarteritic anterior ischaemic optic neuropathy (NAION) in type 2 diabetes, examining treatment recency and cumulative duration. Methods This nationwide registry‐based nested case–control study utilizedz Danish health registries (1996 ...
Siar Niazi, Filip Gnesin, Baker Nawfal Jawad, Zia Niazi, Puriya Daniel Wuertz Yazdanfard, Anne P. Toft‐Petersen, Kathrine Kold Sørensen, Amani Meaidi, Yousif Subhi, Christian Torp‐Pedersen   +9 more
wiley   +1 more source

Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype. [PDF]

Front Immunol
Horváth D, Pénzes Z, Molnár P, Rebenku I, Vereb G, Szántó M, Muzsai S, Szegedi A, Dajnoki Z, Pázmándi K, Fekete T, Bácsi A, Szöllősi AG.   +12 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Correlation of Natriuretic Peptides with Invasively Measured Intracardiac Filling Pressures in Patients With Cancer. [PDF]

JACC CardioOncol
Fatakdawala MM, Ryoo Ali HJ, Song J, Irizarry-Caro JA, Faiz SA, Kumar S, Yusuf SW, Durand JB, Iliescu C, Palaskas N, Deswal A, Koutroumpakis E.   +11 more
europepmc   +1 more source

New biosensors and transgenic mice for multiplex cGMP imaging

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a versatile second messenger that is important for human (patho‐)physiology and pharmacotherapy. Live‐cell imaging of cGMP with biosensors allows to elucidate its spatiotemporal dynamics in real time under close‐to‐native conditions. However, to monitor two separate cGMP pools or cGMP/cAMP
Markus Wolters, Martin Thunemann, Barbara Birk, Susanne Feil, Viacheslav O. Nikolaev, Moritz Lehners, Robert Feil   +6 more
wiley   +1 more source

Natriuretic Peptides as a Predictor for Delirium After Cardiac Surgery: A Prospective Observational Study. [PDF]

J Clin Med
Huisinga C, Struck E, Mihatsch L, Heyn J, Hagl C, Zwissler B, von Dossow V, Saller T.   +7 more
europepmc   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Acute dyspnoea in cancer patients: Prevalence of acute heart failure, resource use and diagnostic accuracy of natriuretic peptides. [PDF]

Eur J Heart Fail
Bima P, Wussler D, Lopez-Ayala P, Belkin M, Nowak A, Lin X, Strebel I, Sgueglia F, Michou E, Papachristou A, Chollet L, Popescu C, Kozhuharov N, Shrestha S, Kuster G, Rentsch K, Von Eckardstein A, Binder M, Mahfoud F, Breidthardt T, Mueller C.   +20 more
europepmc   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu, Johannes Reiner, Franz Hofmann, Azam Salari, Ursula Seidler   +4 more
wiley   +1 more source