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HYPERTENSION, 2018
Natriuretic peptides are commonly considered cardiovascular and renal hormones. Indeed, genetic natriuretic peptide deletion promotes arterial hypertension and associated organ damage.1 Conversely, pharmacological natriuretic peptide augmentation lowers ...
J. Jordan +3 more
semanticscholar +1 more source
Natriuretic peptides are commonly considered cardiovascular and renal hormones. Indeed, genetic natriuretic peptide deletion promotes arterial hypertension and associated organ damage.1 Conversely, pharmacological natriuretic peptide augmentation lowers ...
J. Jordan +3 more
semanticscholar +1 more source
Biology of the Natriuretic Peptides
The American Journal of Cardiology, 2008The biology of the natriuretic peptide (NP) system is complex, yet highly phylogenetically preserved. It regulates salt and water handling, promotes vasodilatation, and exerts favorable effects on the heart in the context of processes such as heart failure.
James L. Januzzi +3 more
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American Journal of Kidney Diseases, 2005
Natriuretic peptides are involved in the regulation of volume homeostasis. Their levels generally are increased in the setting of volume expansion and act on multiple effector systems to cause vasodilation and natriuresis in an effort to return volume status back to normal. In patients with end-stage renal disease, the natriuretic capabilities of these
Mitchell H. Rosner, Sergei Joffy
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Natriuretic peptides are involved in the regulation of volume homeostasis. Their levels generally are increased in the setting of volume expansion and act on multiple effector systems to cause vasodilation and natriuresis in an effort to return volume status back to normal. In patients with end-stage renal disease, the natriuretic capabilities of these
Mitchell H. Rosner, Sergei Joffy
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The renal and cardiovascular effects of natriuretic peptides.
Advances in Physiology Education, 2017The landmark report by de Bold et al. in 1981 signified the heart as one of the endocrine organs involved in fluid and salt balance (de Bold AJ, Borenstein HB, Veress AT, Sonnenberg H. Life Sci 28: 89-94, 1981). Atrial natriuretic peptide (ANP) and brain
P. Wong, Jun Guo, Ai-dong Zhang
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Natriuretic peptides and hypertension
Current Opinion in Nephrology and Hypertension, 1996Natriuretic peptides are produced in the brain, heart and vasculature, and cause vasodilation, sodium excretion, and diuresis. Recent advances indicate that they play important roles in blood-pressure homeostasis, both in normal and in pathophysiological conditions.
Elzbieta Biesiada +2 more
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Physiology of Natriuretic Peptides
Journal of Internal Medicine, 1994De Bold’s discovery 16 yr ago of an atrial tissue factor (1) with strong natriuretic activity understandably captured the imagination of renal physiologists seeking the elusive “third factor” (2) and new insights into sodium regulation. However, as well as natriuresis, de Bold’s original experiments showed that the atrial extract also caused ...
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Journal of Cardiothoracic Anesthesia, 1989
This report has reviewed some of the cardiovascular aspects of ANP. The emergence of the heart as an endocrine organ requires that numerous questions be asked with regard to the importance of ANP to anesthesia and surgery. It is clear that the interaction of the hormone with other vasoactive compounds, including anesthetic agents, requires further ...
R. W. McIntyre, Debra A. Schwinn
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This report has reviewed some of the cardiovascular aspects of ANP. The emergence of the heart as an endocrine organ requires that numerous questions be asked with regard to the importance of ANP to anesthesia and surgery. It is clear that the interaction of the hormone with other vasoactive compounds, including anesthetic agents, requires further ...
R. W. McIntyre, Debra A. Schwinn
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The natriuretic peptides in hypertension
Current Opinion in CARDIOLOGY, 1995The natriuretic peptide family consists of three members: atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Atrial and brain natriuretic peptides possess similar effects, causing natriuresis, vasodilation, and suppression of the renin-angiotensin-aldosterone system.
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The natriuretic-peptide family
The Lancet, 1997The discovery in the early 1980s of atrial natriuretic peptide, a circulating peptide with natriuretic/diuretic and vasorelaxant properties was greeted with excitement since the existence of a humoral link between heart and kidney had long been predicted.
Juliana Redondo +2 more
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The Natriuretic Peptides for Hypertension Treatment
High Blood Pressure & Cardiovascular Prevention, 2021Hypertension is a common pathological condition predisposing to a higher occurrence of cardiovascular diseases and events. Unfortunately, treatment of hypertension is still suboptimal worldwide. More efforts are needed to implement the availability of anti-hypertensive drugs.
Rubattu S., Gallo G.
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