Biotechnology, Bioengineering and Applications of Bacillus Nattokinase
Thrombosis has threatened human health in past decades. Bacillus nattokinase is a potential low-cost thrombolytic drug without side-effects and has been introduced into the consumer market as a functional food or dietary supplement.
Li Yuan +3 more
doaj +3 more sources
NATTOKINASE – USES AND BENEFITS [PDF]
Nattokinase has been one of the most widely discussed and researched extracellular enzymes since it was first introduced in 2005. Nattokinase belongs to the subtilisin family and is a proteolytic enzyme (serine protease) with a powerful fibrinolytic ...
M. Hristova
doaj +2 more sources
Nattokinase: A hope in cardiovascular therapy and more [PDF]
Nattokinase is a fibrinolytic enzyme identified and isolated in 1987 from a specific Japanese food called natto (a kind of vegetable cheese). Since its discovery and until now, nattokinase has been studied experimentally and clinically almost exclusively
Dan-Dominic IONESCU
doaj +2 more sources
Advance on Nattokinase Microbial Production and Physiological Function
With the improvement of people’s living standard, the number of patients with thromboembolism is increasing gradually. Among the existing thrombotic drugs, nattokinase attracts great attention due to its advantages of long half-life, strong specificity ...
Mingjing YAO +9 more
doaj +2 more sources
Nattokinase production: Medium components and feeding strategy studies [PDF]
In the present study, the effect of nutrients on nattokinase activity during the fermentation of Bacillus subtilis natto was investigated. The highest nattokinase activity of 587 U/mL was obtained in fermenter for a media consisting of yeast ...
Berenjian Aydin +4 more
doaj +2 more sources
Nattokinase historical sketch on experimental and clinical evidence
Nattokinase (NK) is a protease derived from food used mainly in the Japanese diet that has several properties. The main activity is related to improving fibrinolytic activities. Other activities have been demonstrated in the regulation of blood pressure
Pierpaolo Di Micco +7 more
doaj +2 more sources
Natural serine proteases and their applications in combating amyloid formation [PDF]
Background and purpose: Amyloidosis is a group of diseases including diabetes type II and neurological disorders, such as Alzheimer’s disease, Parkinson’s disease, prion disease, etc., where a common trait is observed; accumulation of misfolded protein ...
Sanjay Metkar +3 more
doaj +2 more sources
Lipid-lowering, antihypertensive, and antithrombotic effects of nattokinase combined with red yeast rice in patients with stable coronary artery disease: a randomized, double-blinded, placebo-controlled trial [PDF]
Nattokinase (NK) and red yeast rice (RYR) are both indicated for their potential in cardiovascular disease prevention and management, but their combined effects especially in coronary artery disease (CAD) are scarcely examined.
Man Liu +11 more
doaj +2 more sources
Nattokinase crude extract enhances oral mucositis healing [PDF]
Abstract Background Nattokinase (NK) is a promising alternative in the prevention and treatment of cardiovascular diseases due to its potent fibrinolytic activity. In this study, we investigated the effect of crude nattokinase extract on the healing of acetic acid-induced oral mucositis in mice.
Junyao Zhang +7 more
openaire +3 more sources
Nattokinase-Associated Hemoperitoneum in an Elderly Woman [PDF]
The consumption of herbal supplements has become increasingly popular the United States. One such herbal supplement that is available at pharmacies and grocery stores is nattokinase. Nattokinase, a byproduct of soybean fermentation, may have some thrombolytic properties.
Ramachandran, Lintu +4 more
openaire +2 more sources

