Results 31 to 40 of about 792 (145)
Shipin gongye ke-ji, 2022 In order to improve the yield of nattokinase and promote its industrial production and application, Bacillus subtilis was isolated from fresh natto from different producing areas, and the strain with larger ratio of hydrolysis circle to colony was ...
Xueqin ZHOU, Liangzhong LIU
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BIỂU HIỆN GEN NAT05 MÃ HÓA NATTOKINASE TRONG BACILLUS SUBTILIS BD170
Tạp chí Khoa học Đại học Huế: Khoa học Tự nhiên, 2021 Nattokinase, một serine protease có trong sản phẩm Natto truyền thống của Nhật Bản, có khả năng làm tan đặc hiệu các sợi fibrin gây đông máu và rất có ích trong việc phân hủy huyết khối nội sinh ở người.
Nguyen Thi Anh Thu, Ho Thi Trang
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X-ray structure determination and deuteration of nattokinase [PDF]
Journal of Synchrotron Radiation, 2013 Nattokinase (NK) is a strong fibrinolytic enzyme, which is produced in abundance by Bacillus subtilis natto. Although NK is a member of the subtilisin family, it displays different substrate specificity when compared with other subtilisins. The results of molecular simulations predict that hydrogen arrangements around Ser221 at the active site probably
Yanagisawa, Yasuhide +10 more
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Preparation and evaluation of nattokinase-loaded self-double-emulsifying drug delivery system
Asian Journal of Pharmaceutical Sciences, 2015 In the present study, we prepared nattokinase-loaded self-double-emulsifying drug delivery system (SDEDDS) and investigated its preliminary pharmacodynamics.
Xiaona Wang +4 more
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Effect of Fermentation Parameters on Natto and Its Thrombolytic Property
Foods, 2021 Natto is a popular food because it contains a variety of active compounds, including nattokinase. Previously, we discovered that fermenting natto with the combination of Bacillus subtilis GUTU09 and Bifidobacterium animalis subsp. lactis BZ25 resulted in
Yun Yang +6 more
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Effects of Nattokinase on Whole Blood Viscosity and Mortality
Türk Yoğun Bakim Derneği Dergisi, 2011 Objective: Nattokinase is a serin protease having potent fibrinolytic effect derived from fermentation of boiled soy bean by the use of Basillus Subtilis Natto. The aim of this experimental study is to investigate the effects of intragastric Nattokinase (
Melike Cengiz +7 more
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Foods, 2022 Nattokinase is a potential new thrombolytic drug because of its strong thrombolytic effect, high safety, and low cost. However, there is no research reporting on bile salt-tolerant nattokinase-producing probiotics.
Yuan Li +4 more
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BioTechnologia, 2018 Nattokinase, the fibrinolytic serine protease, has been shown to be beneficial in preventing strokes caused due to blood clots. Therefore, synthesis of recombinant nattokinase in a host system, which can be both safe for human consumption as well as ...
Nguyen Thi Anh Thu +8 more
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BMC Biotechnology, 2021 Background Nattokinase is a fibrinolytic enzyme that has huge market value as a nutritional supplement for health promotion. In order to increase nattokinase yields, fermentation conditions, strains, cultivation media, and feeding strategies have been ...
Yan Guangbo +6 more
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Safety evaluation of the food enzyme subtilisin from the genetically modified <i>Bacillus subtilis</i> strain DP-Ezx62. [PDF]
EFSA JAbstract The food enzyme subtilisin (EC 3.4.21.62) is produced with the genetically modified Bacillus subtilis strain DP‐Ezx62 by Danisco US Inc. The production strain of the food enzyme contains multiple copies of a known antimicrobial resistance gene, and consequently, it does not fulfil the requirements for the qualified presumption of safety (QPS ...
EFSA Panel on Food Enzymes (FEZ) +17 more
europepmc +2 more sources